Phenol, 5-chloro-2-[4-[(2-hydroxy-2-methylpropyl)amino]pyrido[3,4-d]pyridazin-1-yl]- manufacturers
- NLRP3-IN-11
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- $44.00
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2026-07-15
- CAS:2769040-91-5
- Purity: 99.99%
- Supply Ability: 10g
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| | Phenol, 5-chloro-2-[4-[(2-hydroxy-2-methylpropyl)amino]pyrido[3,4-d]pyridazin-1-yl]- Basic information |
| | Phenol, 5-chloro-2-[4-[(2-hydroxy-2-methylpropyl)amino]pyrido[3,4-d]pyridazin-1-yl]- Chemical Properties |
| Boiling point | 613.2±50.0 °C(Predicted) | | density | 1.404±0.06 g/cm3(Predicted) | | pka | 7.18±0.40(Predicted) | | form | Solid | | color | White to off-white |
| | Phenol, 5-chloro-2-[4-[(2-hydroxy-2-methylpropyl)amino]pyrido[3,4-d]pyridazin-1-yl]- Usage And Synthesis |
| Uses | NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1]. | | IC 50 | NLRP3: <0.3 μM (IC50) | | References | [1] HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1. |
| | Phenol, 5-chloro-2-[4-[(2-hydroxy-2-methylpropyl)amino]pyrido[3,4-d]pyridazin-1-yl]- Preparation Products And Raw materials |
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