Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-

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Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl- manufacturers
Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl- Basic information
Product Name:Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-
Synonyms:Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-;Vasopressin V2 receptor antagonist 1
CAS:2648650-50-2
MF:C33H37ClN4O4
MW:589.12
EINECS:
Product Categories:
Mol File:2648650-50-2.mol
Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl- Structure
Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl- Chemical Properties
Boiling point 741.2±60.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
pka13.00±0.70(Predicted)
Safety Information
MSDS Information
Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl- Usage And Synthesis
UsesVasopressin V2 receptor antagonist 1 (Compound 4g) is a vasopressin V2 receptor (V2R) antagonist with a Ki of 3.8 nM. Vasopressin V2 receptor antagonist 1 can be used for autosomal dominant polycystic kidney disease (ADPKD) research[1].
References[1] Haoran Zhang, et al. Long Residence Time at the Vasopressin V2 Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease. J Med Chem. 2022 Apr 1. DOI:10.1021/acs.jmedchem.2c00011
Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl- Preparation Products And Raw materials
Tag:Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-(2648650-50-2) Related Product Information
Benzamide, N-[4-[[7-chloro-2,3,4,5-tetrahydro-5-[[3-(4-morpholinyl)-3-oxopropyl]amino]-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl- (2S,4R)-1-[(R)-5-Chloro-1-(2,4-dimethoxy-benzenesulfonyl)-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-pyrrolidine-2-carboxylic acid dimethylamide Imidafenacin WAY-151932 Terlipressin Diacetate Salt 2-(3-Chloro-4-fluorophenyl)-N-(1-methylethyl)-6-[3-(4-morpholinyl)propoxy]-4-oxo-pyrido[2,3-d]pyrimidine-3(4H)-acetamide hydrochloride