trimethylcolchicinic acid methyl ether manufacturers
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| | trimethylcolchicinic acid methyl ether Basic information |
| Product Name: | trimethylcolchicinic acid methyl ether | | Synonyms: | trimethylcolchicinic acid methyl ether;(S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one;Deacetylcolchicine;(7S)-7-Amino-1,2,3,10-Tetramethoxy-6,7-Dihydro-5H-Benzo[g]Heptalen-9-One;(-)-7-Deacetylcolchicine;(7S)-7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one;NSC 201400;7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one | | CAS: | 3476-50-4 | | MF: | C20H23NO5 | | MW: | 357.4 | | EINECS: | | | Product Categories: | Amines;Chiral Reagents;Heterocycles;Amines, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 3476-50-4.mol |  |
| | trimethylcolchicinic acid methyl ether Chemical Properties |
| Boiling point | 490.03°C (rough estimate) | | density | 1.2532 (rough estimate) | | refractive index | 1.5614 (estimate) | | storage temp. | -20°C Freezer, Under Inert Atmosphere | | solubility | DMSO: 25mg/mL; Ethanol: 25mg/mL | | form | A crystalline solid | | pka | 8.62±0.40(Predicted) |
| | trimethylcolchicinic acid methyl ether Usage And Synthesis |
| Chemical Properties | Yellow Solid | | Uses | An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. | | Definition | ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides. |
| | trimethylcolchicinic acid methyl ether Preparation Products And Raw materials |
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