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| | PSMA targeting peptide Basic information |
| Product Name: | PSMA targeting peptide | | Synonyms: | PSMA targeting peptide;PSMA targeting peptide、PSMA-1;L-Serine, glycyl-L-arginyl-L-phenylalanyl-L-leucyl-L-threonylglycylglycyl-L-threonylglycyl-L-arginyl-L-leucyl-L-leucyl-L-arginyl-L-isoleucyl- | | CAS: | 2042750-71-8 | | MF: | C70H122N24O19 | | MW: | 1603.87 | | EINECS: | | | Product Categories: | | | Mol File: | 2042750-71-8.mol |  |
| | PSMA targeting peptide Chemical Properties |
| density | 1.432±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 3.015±0.10(predicted) | | Sequence | Gly-Arg-Phe-Leu-Thr-Gly-Gly-Thr-Gly-Arg-Leu-Leu-Arg-Ile-Ser |
| | PSMA targeting peptide Usage And Synthesis |
| Uses | PSMA-1 is a PSMA targeting peptide (GRFLTGGTGRLLRIS) and can be used for for targeted delivery of glucose-regulated protein (GRP)-silencing siRNAs in PCa cells. PSMA-1 is selected and polyarginine sequences R6 or R9 were added at the C terminus to generate the CTPs. FITC labeling of the peptide with an aminohexanoic acid (Ahx) linker at the N terminus produced FITC-PSMA-1，to track PSMA binding on PCa cells[1]. | | References | [1] Christopher N Cultrara, et al. Size Matters: Arginine-Derived Peptides Targeting the PSMA Receptor Can Efficiently Complex but Not Transfect siRNA. Mol Ther Nucleic Acid. 019 Dec 6:18:863-870. DOI:10.1016/j.omtn.2019.10.013 |
| | PSMA targeting peptide Preparation Products And Raw materials |
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