| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
|
| | 2-(1H-Indol-2-yl)aniline Basic information |
| | 2-(1H-Indol-2-yl)aniline Chemical Properties |
| Melting point | 154-155 °C(lit.) | | Boiling point | 437.9±20.0 °C(Predicted) | | density | 1.229±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, protect from light | | pka | 16.53±0.30(Predicted) | | Appearance | Light brown to brown Solid | | InChI | 1S/C14H12N2/c15-12-7-3-2-6-11(12)14-9-10-5-1-4-8-13(10)16-14/h1-9,16H,15H2 | | InChIKey | IAKRGXQCKYFJCB-UHFFFAOYSA-N | | SMILES | Nc1ccccc1-c2cc3ccccc3[nH]2 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2-(1H-Indol-2-yl)aniline Usage And Synthesis |
| Uses | Reactant in:
- cascade reactions of benzopyranylidenemalonates with mono- and dinucleophiles
Reactant for preparation of:
- Mono-, bis-indolo[1,2-c]quinazolines as antimicrobial agents
- Isocryptolepine alkaloid with antimalarial activity
- Cyanoindolo[3,2-c]quinolines and benzimidazo[1,2-c]quinazolines as antitumor agents
| | General Description | 2-(2-Aminophenyl)indole is an indole derivative. It has been reported as an amination reagent. 2-(2-Aminophenyl)indole undergoes condensation with 4,5-dichloro-1,2,3-dithiazolium chloride (Appel salt) to afford new 6-cyanoindolo[3,2-c]quinoline derivatives, having pharmacological applications. |
| | 2-(1H-Indol-2-yl)aniline Preparation Products And Raw materials |
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