4,4'-DICHLOROBUTYROPHENONE manufacturers
- 4,4"-DICHLOROBUTYROPHENONE
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- $15.00 / 1KG
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2021-08-12
- CAS:40877-09-6
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 4,4'-DICHLOROBUTYROPHENONE Basic information |
| Product Name: | 4,4'-DICHLOROBUTYROPHENONE | | Synonyms: | GAMMA,P-DICHLOROBUTYROPHENONE;GAMMA,4-DICHLOROBUTYROPHENONE;LABOTEST-BB LT00848184;4-CHLORO-1-(4-CHLOROPHENYL)-1-BUTANONE;4-CHLORO-1-(4-CHLOROPHENYL)-1-OXOBUTANE;4-chloro-1-(4-chlorophenyl)butan-1-one;4',γ-Dichlorobutyrophenone;4-Chlorophenyl 3-chloropropyl ketone | | CAS: | 40877-09-6 | | MF: | C10H10Cl2O | | MW: | 217.09 | | EINECS: | 255-123-4 | | Product Categories: | | | Mol File: | 40877-09-6.mol |  |
| | 4,4'-DICHLOROBUTYROPHENONE Chemical Properties |
| Melting point | 29-30 °C | | Boiling point | 153-155 °C(Press: 2 Torr) | | density | 1.2372 (estimate) | | refractive index | 1.5600 | | form | Pellets | | color | White | | BRN | 879782 | | CAS DataBase Reference | 40877-09-6(CAS DataBase Reference) |
| | 4,4'-DICHLOROBUTYROPHENONE Usage And Synthesis |
| Chemical Properties | clear yellow to brown liquid after melting | | Synthesis | To a dry reaction tube were sequentially added 0.2 mmol 1-(4-chlorophenyl)cyclobutanol, 0.02 mmol manganese dichloride (MnCl2), 0.6 mmol trimethylsilyl chloride (TMSCl), 0.4 mmol 2-iodobenzoic acid and 1 mL acetonitrile (MeCN). The reaction mixture was stirred at 50°C for 7 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The crude product was purified by column chromatography using a solvent mixture of petroleum ether and ethyl acetate as eluent (20:1 v/v). The final product was 4,4'-dichlorobutyrophenone in 88.2% yield and 98% purity. | | References | [1] Organic Letters, 2016, vol. 18, # 4, p. 684 - 687
[2] Patent: CN106008181, 2016, A. Location in patent: Paragraph 0039-0041 |
| | 4,4'-DICHLOROBUTYROPHENONE Preparation Products And Raw materials |
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