2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-

Company Name:	Shanghai Han-Xiang Chemical Co., Ltd.
Tel:	17754423994
Email:	candy@biochempartner.com

Company Name:	ShangHai ChuanQian Chemcial Technique Centre
Tel:	15869524721
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2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy- Basic information

Product Name:	2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-
Synonyms:	2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-;4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one;4-Acetyl-1-(4-Chloro-2-Fluorophenyl)-5-Cyclohexyl-1,5-Dihydro-3-Hydroxy-2H-Pyrrol-2-One;4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1H-pyrrol-2(5H)-one;187381;CCR2-RA
CAS:	512177-31-0
MF:	C18H19ClFNO3
MW:	351.8
EINECS:
Product Categories:
Mol File:	512177-31-0.mol

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy- Chemical Properties

Safety Information

MSDS Information

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy- Usage And Synthesis

Uses	CCR2-RA is a allosteric antagonist of chemokine (C-C motif) receptor 2 (CCR 2), and it can be used in cancer research[1].
IC 50	CCR2
References	[1] Lisa S den Hollander, et al. CC chemokine receptor 2 is allosterically modulated by sodium ions and amiloride derivatives through a distinct sodium ion binding site. Biochem Pharmacol. 2024 Nov:229:116464. DOI:10.1016/j.bcp.2024.116464

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy- Preparation Products And Raw materials

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