2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-

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2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Suppliers list
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2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- manufacturers

  • CCR2-RA-[R]
  • CCR2-RA-[R] pictures
  • $39.00
  • 2026-07-27
  • CAS:512177-83-2
  • Purity: 99.70%
  • Supply Ability: 10g
  • CCR2-RA-[R]
  • CCR2-RA-[R] pictures
  • $39.00
  • 2026-07-27
  • CAS:512177-83-2
  • Purity: 99.70%
  • Supply Ability: 10g
2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Basic information
Product Name:2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-
Synonyms:187305;(R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1H-pyrrol-2(5H)-one;2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-;(R)-4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one;(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one;CCR,Inhibitor,inhibit,CCR-2-RA-[R],CC chemokine receptor,CCR2RA[R],CCR2 RA [R;4-ACETYL-1-(4-CHLORO-2-FLUOROPHENYL)-5-CYCLOHEXYL-3-HYDROXY-5H-PYRROL-2-ONE;CCR2-RA-[R], 10 mM in DMSO
CAS:512177-83-2
MF:C18H19ClFNO3
MW:351.8
EINECS:
Product Categories:
Mol File:512177-83-2.mol
2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Structure
2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Chemical Properties
Boiling point 482.6±45.0 °C(Predicted)
density 1.383±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 1 mg/ml
form A crystalline solid
pka4.50±1.00(Predicted)
color White to off-white
Safety Information
MSDS Information
2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Usage And Synthesis
Uses(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one, is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM.
IC 50CCR2: 103 nM (IC50)
2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Preparation Products And Raw materials
Tag:2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-(512177-83-2) Related Product Information
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