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| | 8-Ma-cAMP sodium salt Basic information |
| Product Name: | 8-Ma-cAMP sodium salt | | Synonyms: | 8-METHYLAMINOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-methylaminoadenosine-3’,5’cyclicmonophosphate(8-ma-camp),sodiumsalt;8-MA-CAMP;8-METHYLAMINOADENOSINE 3':5'-CYCLIC MONO PHOSPHATE;8-Methylaminoadenosine-3'',5''-cyclic monophosphoric acid sodium salt;8-(METHYLAMINO)-ADENOSINE-3'',5''-CYCLIC-MONOPHOSPHORIC ACID CRYSTALLINE;Adenosine, 8-(methylamino)-, cyclic 3',5'-(hydrogen phosphate);methyl (2S,3S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-carboxylate | | CAS: | 33823-18-6 | | MF: | C11H15N6O6P | | MW: | 358.25 | | EINECS: | | | Product Categories: | | | Mol File: | 33823-18-6.mol |  |
| | 8-Ma-cAMP sodium salt Chemical Properties |
| Boiling point | 707.0±70.0 °C(Predicted) | | density | 2.34±0.1 g/cm3(Predicted) | | storage temp. | −70°C | | solubility | H2O: freely soluble | | form | solid | | pka | 1.00±0.60(Predicted) | | color | white |
| | 8-Ma-cAMP sodium salt Usage And Synthesis |
| Uses | 8-MA-cAMP (8-Methylamino-cAMP) is a cyclic AMP analog that acts as a site-selective PKA agonist with similar affinity for the B site of type I and type II protein kinase A. 8-MA-cAMP is used in conjunction with priming analogs that show site A preference, such as 8-piperidinyl cAMP, to achieve selective stimulation of type I[1]. | | References | [1] Schwede, et al. 8-Substituted cAMP analogues reveal marked differences in adaptability, hydrogen bonding, and charge accommodation between homologous binding sites (AI/AII and BI/BII) in cAMP kinase I and II. Biochemistry 39.30 (2000): 8803-8812. DOI:10.1021/bi000304y |
| | 8-Ma-cAMP sodium salt Preparation Products And Raw materials |
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