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Adenosine 3',5'-cyclic monophosphate sodium salt

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Adenosine 3',5'-cyclic monophosphate sodium salt Basic information
Product Name:Adenosine 3',5'-cyclic monophosphate sodium salt
Synonyms:ADENOSINE-3',5'-CYCLIC PHOSPHATE SODIUM;ADENOSINE-3',5'-MONOPHOSPHORIC ACID SODIUM SALT;ADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM;ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT;ADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;A-3:5-MP, SODIUM SALT;3',5'-CYCLIC AMP SODIUM SALT;3:5-CAMP, NA
CAS:37839-81-9
MF:C10H13N5NaO6P
MW:353.21
EINECS:253-328-3
Product Categories:Biochemistry;Nucleosides, Nucleotides & Related Reagents;Nucleotides and their analogs;API;Nucleoside Mono
Mol File:37839-81-9.mol
Adenosine 3',5'-cyclic monophosphate sodium salt Structure
Adenosine 3',5'-cyclic monophosphate sodium salt Chemical Properties
storage temp. -20°C
solubility H2O: 50 mg/mL
form powder
color white
Water Solubility Soluble in water (50 mg/ml).
BRN 54612
Stability:Hygroscopic
InChI1S/C10H12N5O6P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7;/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
InChIKeyBXJBFCKTIWRKMQ-MCDZGGTQSA-M
SMILES[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O
CAS DataBase Reference37839-81-9
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 2
RTECS AU7357900
F 10-21
HS Code 29349990
Storage Class11 - Combustible Solids
MSDS Information
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SigmaAldrich English
Adenosine 3',5'-cyclic monophosphate sodium salt Usage And Synthesis
Chemical PropertiesWhite crystalline powder
UsesAdenosine 3',5'-cyclic monophosphate sodium salt is an Adenosine (A280400) derivative useful as anticancer agent.
UsesAdenosine 3,5-cyclic monophosphate sodium salt monohydrate is used as an activator of protein kinase A (PKA) . A key regulator of many cellular reactions. Released in response to hormonal stimulation. . Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes.
Biochem/physiol ActionsNaturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.
Adenosine 3',5'-cyclic monophosphate sodium salt Preparation Products And Raw materials
Tag:Adenosine 3',5'-cyclic monophosphate sodium salt(37839-81-9) Related Product Information
Cyclic AMP Adenosine-5'-diphosphate disodium salt ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& ATP disodium salt ADENOSINE5'-MONOPHOSPHATESODIUMSALT Adenosine 5'-monophosphate monohydrate ADP 5'-Tosyladenosine cytidine monophosphate-N-glycoloylneuraminic acid Adenosine Adenosine 3',5'-cyclic monophosphate sodium salt Bucladesine sodium 8-OH-CAMP SODIUM SALT 8-CPT-CAMP SODIUM SALT 8-CHLORO-CAMP N6,2'-O-DISUCCINYLADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT 2'-O-MB-CAMP SODIUM SALT 8-BR-CAMP SODIUM SALT,8-BROMO-CAMP, SODIUM SALT