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| | UNCARINE D Basic information |
| Product Name: | UNCARINE D | | Synonyms: | (3β,7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester;Nsc113094;Speciophylline (Uncarine D);Uncarin D;UNCARINE D;Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aR,10'aS)-;SPECIOPHYLLINE | | CAS: | 4697-68-1 | | MF: | C21H24N2O4 | | MW: | 368.43 | | EINECS: | | | Product Categories: | | | Mol File: | 4697-68-1.mol |  |
| | UNCARINE D Chemical Properties |
| Melting point | 183~184℃ | | Boiling point | 555.2±50.0 °C(Predicted) | | density | 1.33 | | pka | 13.56±0.60(Predicted) |
| | UNCARINE D Usage And Synthesis |
| Description | One of the alkaloids isolated from the leaves of Mitragyna speciosa, the structure
of the base has been determined from the NMR spectrum which demonstrates
that the alkaloid has a cis DIE ring junction and a conformation such that the
oxindole ring deshields the ester methoxyl group. | | Uses | Uncarine D is a compound extracted from Uncaria tomentosa leaves. The compounds extracted from these leaves have exhibited immunomodulating, antiinflammatory and anti-cancer activity, attributed to the presence of tetra/pentacyclic oxindole alkaloids. | | Definition | ChEBI: Uncarine D is a member of indolizines. | | References | Beckett et al., Sci. Pharm., Froc., 25th (1965) |
| | UNCARINE D Preparation Products And Raw materials |
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