- UNCARINE C
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- $2.20 / 1KG
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2024-10-22
- CAS:5629-60-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1KG/10KG/100KG
- UNCARINE C
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- $0.00 / 25kg
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2024-04-12
- CAS:5629-60-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
- Peiminine
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- $0.00 / 25kg
-
2024-04-12
- CAS:5629-60-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
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| | UNCARINE C Basic information |
| Product Name: | UNCARINE C | | Synonyms: | PTEROPODINE;UNCARINE C;(20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester;2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester;methyl 1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate;methyl 1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate;Isospeciophylline;Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3R,4'aS,5'aS,10'aS)- | | CAS: | 5629-60-7 | | MF: | C21H24N2O4 | | MW: | 368.43 | | EINECS: | | | Product Categories: | | | Mol File: | 5629-60-7.mol |  |
| | UNCARINE C Chemical Properties |
| Melting point | 217-219℃ | | density | 1.33±0.1 g/cm3 (20 ºC 760 Torr) | | form | Solid | | color | White to off-white |
| | UNCARINE C Usage And Synthesis |
| Description | Isolated from Uncaria pteropoda, this alkaloid is probably stereoisomeric withMitraphylline (q.v.). It forms colourless plates when crystallized from MeOH and
has [α]29DJ 9 - 102.5° (c 1.0, CHC13). The ultraviolet spectrum in MeOH has an
absorption maximum at 246 mp. with a shoulder at 280 mp.. A crystalline picrate,
m.p. 143-6°C; [α]D - 9.6° (c 0.5, EtOH) and a methiodide, m.p. 209-211°C
after softening at 204°C; [α]D - 149° (c 0.53, EtOH) have been prepared. A
solution of the alkaloid in pyridine forms an equilibrium mixture with 70 per
cent isopteropodine when heated. | | Uses | Uncarine C is a compound extracted from Uncaria tomentosa leaves. The compounds extracted from these leaves have exhibited immunomodulating, antiinflammatory and anti-cancer activity, attributed to the presence of tetra/pentacyclic oxindole alkaloids. | | Definition | ChEBI: Uncarine C is a member of indolizines. | | References | Yeoh, Chan, Morsingh., Tetrahedron Lett., 931 (1966)
Chan, Morsingh, Yeoh., 1. Chem. Soc., C, 2245 (1966)
Stereochemistry:
Shamma et al., 1. Amer. Chem. Soc., 89, 1739, 2799 (1967) |
| | UNCARINE C Preparation Products And Raw materials |
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