1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride

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Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
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1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride manufacturers

  • WAY 629
  • WAY 629 pictures
  • $1980.00
  • 2026-05-11
  • CAS:57756-45-3
  • Purity:
  • Supply Ability: 10g
1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride Basic information
Product Name:1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride
Synonyms:WAY 629 HYDROCHLORIDE;4,5,6,7,9,10,11,12-Octahydro[1,4]diazepino[6,7,1-jk]carbazole;[1,4]Diazepino[6,7,1-jk]carbazole, 4,5,6,7,9,10,11,12-octahydro-;WAY 629 hydrochlorid;1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride
CAS:57756-45-3
MF:C15H18N2
MW:226.32
EINECS:
Product Categories:Serotonin receptor
Mol File:57756-45-3.mol
1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride Structure
1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride Chemical Properties
Melting point 114-115℃
storage temp. Desiccate at +4°C
Safety Information
MSDS Information
1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride Usage And Synthesis
UsesWAY 629 is a selective SR-2C agonist. Potent and efficacious 5-HT2C receptor agonists.
DefinitionChEBI: LSM-3233 is a member of carbazoles.
Biological ActivitySelective 5-HT 2C agonist. K i values are 56, 2350, 1575 and 815 nM for human recombinant 5-HT 2C , 5-HT 2A , 5-HT 6 and 5-HT 7 receptors respectively. Stimulates intracellular Ca 2+ mobilization in CHO cells expressing human 5-HT 2C receptors (EC 50 = 72 nM). Reduces food intake in rats.
in vivo

WAY 629 (30 mg/kg; i.p.) decreases feeding behavior in rats[1].
WAY 629 (21 mg/kg; i.p.) decreases the expression of NPY mRNA in mice brains[2].

Animal Model:WT mice[2]
Dosage:21 mg/kg
Administration:I.p.
Result:Decreased the expression of NPY mRNA.
IC 505-HT2C Receptor: 426 nM (EC50); 5-HT2A Receptor: 260000 nM (EC50)
1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride Preparation Products And Raw materials
Tag:1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride(57756-45-3) Related Product Information
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