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Bupropion morpholinol

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Bupropion morpholinol Basic information
Product Name:Bupropion morpholinol
Synonyms:(2R,3R)-2-(-3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol;2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol;Bupropion Morpholinol (Mixture of stereoisoMers);2-(3-Chlorophenyl)-3,5,5-triMethyl-;Bupropion Impurity 12;Bupropion Hydroxy Cyclic Impurity;Bupropion Morpholinol (Hydroxy Bupropion);Bupropion Morpholinol Racemate
CAS:357399-43-0
MF:C13H18ClNO2
MW:255.74
EINECS:
Product Categories:Metabolite;Isotope;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:357399-43-0.mol
Bupropion morpholinol Structure
Bupropion morpholinol Chemical Properties
Melting point 121-123°C
Boiling point 386.6±42.0 °C(Predicted)
density 1.144±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.50 mg/ml
form A crystalline solid
pka11.90±0.60(Predicted)
color White to off-white
InChIInChI=1S/C13H18ClNO2/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10/h4-7,9,15-16H,8H2,1-3H3
InChIKeyRCOBKSKAZMVBHT-UHFFFAOYSA-N
SMILESN1C(C)(C)COC(C2=CC=CC(Cl)=C2)(O)C1C
Safety Information
MSDS Information
Bupropion morpholinol Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesA metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3’-chlorophenyl)-355-trimethylmorpholine). See US Pat. # 634.2496
Bupropion morpholinol Preparation Products And Raw materials
Tag:Bupropion morpholinol(357399-43-0) Related Product Information
2-Bromo-3'-chloropropiophenone Bupropion Impurity 3 2-(tert-Butylamino)-3',5'-dichloropropiophenone Hydrochloride 1-(3-Chlorophenyl)-2-hydroxy-1-propanone Bupropion Hydrochloride Related Compound B (15 mg) (2-(tert-butylamino)-3'-bromopropiophenone hydrochloride) 1-(3-Chlorophenyl)-1-hydroxy-2-propanone rac-erythro-Dihydro Bupropion Hydrochloride Bupropion IMpurity Bupropion Hydrochloride Related Compound A (15 mg) (2-(tert-butylamino)-4'-chloropropiophenone hydrochloride) 1-(3-Chlorophenyl)-1,2-propanedione (3S,5S,6S)-Bupropion Impurity 3-Chlorobenzoic acid 3'-Chloropropiophenone (3S,5R,6R)-Bupropion Impurity 3-Deschloro-2-chloro Bupropion Hydrochloride Bupropion-d9 hydrochloride Bupropion morpholinol-d6 Bupropion IMpurity ((3R,5RS,6RS)-6-(3-Chlorophenyl)-6-Hydroxy-5-Methyl-3-ThioMorpholine Carboxylic Acid)