4-Chloro-5-hydroxy-3(2H)-pyridazinone manufacturers
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| | 4-Chloro-5-hydroxy-3(2H)-pyridazinone Basic information | | Uses |
| Product Name: | 4-Chloro-5-hydroxy-3(2H)-pyridazinone | | Synonyms: | 5-Chloro-6-hydroxy-1H-pyridazin-4-one;4-Chloro-5-hydroxypyridazin-3(2H)-one;5-chloro-4-hydroxy-1H-pyridazin-6-one;3(2H)-Pyridazinone, 4-chloro-5-hydroxy-;4-CHLORO-5-HYDROXY-3(2H)-PYRIDAZINONE ISO 9001：2015 REACH;4-Chloro-5-hydroxy-3(2H)-pyridazinone | | CAS: | 64178-58-1 | | MF: | C4H3ClN2O2 | | MW: | 146.53 | | EINECS: | | | Product Categories: | | | Mol File: | 64178-58-1.mol |  |
| | 4-Chloro-5-hydroxy-3(2H)-pyridazinone Chemical Properties |
| Melting point | 270-273 °C(Solv: N,N-dimethylformamide (68-12-2)) | | density | 1.79±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 4.50±1.00(Predicted) | | Appearance | White to off-white Solid |
| | 4-Chloro-5-hydroxy-3(2H)-pyridazinone Usage And Synthesis |
| Uses | 4-Chloro-5-hydroxy-3(2H)-pyridazine is an organic intermediate. | | Synthesis | Wagner et al. reported that it can be prepared from 4,5-dichloropyridazin-3(2H)-one as starting material. 4,5-Dichloropyridazin-3(2H)-one (2 g, 12 mmol) was refluxed in 20 ml of 8N KOH for 6 hours. After acidification with HCl, the reaction mixture was concentrated in vacuum and extracted with ethyl acetate to give 4-chloro-5-hydroxy3(2H)-pyridazine. Yield 0.69 g, 54%. m.p. 267-272°C (from DMF), Lit. 270-273°C. IR: 2300-3340re,b,1650m,1595s,1555shcm-1.1H-NMR(DMSO-d6):δ=7.7 (s HatC-6),12.9(s,b,NH).C4H3C1N2O2(146.5);calcd.C32.78,H2.06,N19.12;foundC32.75,H2.17,N19.06.
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| | 4-Chloro-5-hydroxy-3(2H)-pyridazinone Preparation Products And Raw materials |
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