Fenbendazole-d3 manufacturers
- Fenbendazole-D3
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- $84.00
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2026-07-15
- CAS:1228182-47-5
- Purity:
- Supply Ability: 10g
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| | Fenbendazole-d3 Basic information |
| | Fenbendazole-d3 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: slightly soluble,Methanol: slightly soluble | | form | Solid | | color | Off-white to light yellow | | Major Application | clinical testing | | InChI | 1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)/i1D3 | | InChIKey | HDDSHPAODJUKPD-FIBGUPNXSA-N | | SMILES | [2H]C([2H])([2H])OC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Aquatic Acute 1
Aquatic Chronic 1
Repr. 2
STOT RE 2 |
| | Fenbendazole-d3 Usage And Synthesis |
| Description | Fenbendazole-d3 is intended for use as an internal standard for the quantification of fenbendazole by GC- or LC-MS. Fenbendazole is a benzimidazole anthelmintic. It is active against Giardia in vitro (IC50 = 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection. It also activates HIF-1α and prevents oxidative stress-induced death in primary neurons in vitro. | | Uses | Labelled Fenbendazole (F246750). An anthelmintic (Nematodes). | | References | [1] U M MORGAN R C T J A Reynoldson. Activities of several benzimidazoles and tubulin inhibitors against Giardia spp. in vitro.[J]. Antimicrobial Agents and Chemotherapy, 1993, 37 2: 328-331. DOI: 10.1128/aac.37.2.328
[2] C. SUTER. Prevention and treatment of Encephalitozoon cuniculi infection in rabbits with fenbendazole[J]. Veterinary Record, 2001, 16 1: 478-480. DOI: 10.1136/vr.148.15.478
[3] HOSSEIN ALEYASIN. Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin.[J]. Antioxidants & redox signaling, 2015, 22 2: 121-134. DOI: 10.1089/ars.2013.5595 |
| | Fenbendazole-d3 Preparation Products And Raw materials |
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