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LY-2608204

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Company Name: Shanghai Boyle Chemical Co., Ltd.  
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Company Name: Shanghai Aladdin Bio-Chem Technology Co.,LTD  
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LY-2608204 manufacturers

  • Globalagliatin
  • Globalagliatin pictures
  • $73.00
  • 2026-09-10
  • CAS:1234703-40-2
  • Purity: 99.49%
  • Supply Ability: 10g
  • LY-2608204
  • LY-2608204 pictures
  • $1.00
  • 2019-12-24
  • CAS:1234703-40-2
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 20kg
LY-2608204 Basic information
Product Name:LY-2608204
Synonyms:LY-2608204;(1R,2S)-2-Cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]cyclopropanecarboxamide;(1R,2S)-2-cyclohexyl-1-(4-(cyclopropylsulfonyl)phenyl)-N-(5-((2-(pyrrolidin-1-yl)ethyl)thio)thiazol-2-yl)cyclopropanecarboxaMide;CS-898;LY-2608204; LY 2608204;(1R,2S)-2-Cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]cyclopropanecarboxamide LY 2608204;Cyclopropanecarboxamide, 2-cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]-, (1R,2S)-;LY-2608024
CAS:1234703-40-2
MF:C28H37N3O3S3
MW:559.81
EINECS:
Product Categories:Inhibitors
Mol File:1234703-40-2.mol
LY-2608204 Structure
LY-2608204 Chemical Properties
density 1.35
storage temp. Store at -20°C
solubility ≥28.35 mg/mL in DMSO; insoluble in H2O; ≥26.2 mg/mL in EtOH
form solid
pka8.17±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
LY-2608204 Usage And Synthesis
DescriptionLY2608204 is an activator of glucokinase (GK; EC50 = 42 nM). It stimulates glucose metabolism in INS-1E rat insulinoma cells (mean EC50 = 579 nM). LY2608204 (30 mg/kg) decreases plasma glucose levels in a dose-dependent manner in fasted rats.
UsesGlobalagliatin (LY2608204) is an orally active glucokinase (GK) activator with an EC50 of 42 nM. Globalagliatin also stimulates glucose metabolism in rat insulinoma INS1-E cells with an EC50 of 579 nM. Globalagliatin targets both pancreatic β-cells and hepatocytes. Globalagliatin is promising for research of type 2 diabetes[1][2][3].
targetGK
references[1] kj filipski, bd stevens . glucokinase activators in development .2012 books
LY-2608204 Preparation Products And Raw materials
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