2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Suppliers list

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Email:	ivan@atkchemical.com
Products Intro:	Product Name:SB 657510 CAS:474960-44-6 Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:SB-657510 CAS:474960-44-6 Purity:98.03% Package:1mg;75USD\|5mg;226USD\|10mg;340USD Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Career Henan Chemica Co
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Email:	laboratory@coreychem.com
Products Intro:	Product Name:2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide CAS:474960-44-6 Purity:99% Cherry 0382 Email: cherry@coreychem.com Package:1g;0.37USD

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354;
Email:	support@targetmol.com
Products Intro:	Product Name:SB-657510 CAS:474960-44-6 Purity:98.03% Package:1mg;75USD\|5mg;226USD\|10mg;340USD

Company Name:	Aladdin Scientific
Tel:
Email:	tp@aladdinsci.com
Products Intro:	Product Name:SB 657510 CAS:474960-44-6 Purity:>=98%(HPLC) Package:$454.9/5mg;$771.9/10mg;$1737.9/25mg;$3126.9/50mg;Bulk package Remarks:98%(HPLC)

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide manufacturers

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Basic information

Product Name:	2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide
Synonyms:	2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide;CS-1139;SB 657510;BenzenesulfonaMide, 2-broMo-N-[4-chloro-3-[[(3R)-1-Methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-diMethoxy-;2-bromo-N-[4-chloro-3-[(3R)-1-methylpyrrolidin-3-yl]oxy-phenyl]-4,5-dimethoxy-benzenesulfonamide;SB 657510,SB657510;(R)-2-Bromo-N-(4-chloro-3-((1-methylpyrrolidin-3-yl)oxy)phenyl)-4,5-dimethoxybenzenesulfonamide;SB-657510, 10 mM in DMSO
CAS:	474960-44-6
MF:	C19H22BrClN2O5S
MW:	505.81
EINECS:
Product Categories:
Mol File:	474960-44-6.mol

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Chemical Properties

Boiling point	585.0±60.0 °C(Predicted)
density	1.512±0.06 g/cm3(Predicted)
storage temp.	Store at RT
solubility	DMSO: ≥30mg/mL
pka	6.60±0.10(Predicted)
form	powder
color	white to off-white
InChI	1S/C19H22BrClN2O5S/c1-23-7-6-13(11-23)28-16-8-12(4-5-15(16)21)22-29(24,25)19-10-18(27-3)17(26-2)9-14(19)20/h4-5,8-10,13,22H,6-7,11H2,1-3H3/t13-/m1/s1
InChIKey	KQCZCINJGIRLCD-CYBMUJFWSA-N
SMILES	COc1cc(Br)c(cc1OC)S(=O)(=O)Nc2ccc(Cl)c(O[C@@H]3CCN(C)C3)c2

Safety Information

MSDS Information

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Usage And Synthesis

Uses	SB 657510 is a selective GPR14 (urotensin-II (UT) receptor) antagonist.
Biological Activity	SB 657510 slows development of diabetes-associated atherosclerosis in mouse model of diabetes.1 ', 'SB-657510 is a selective urotensin-II (UT) receptor antagonist. Human urotensin-II (hU-II) is proposed to play a significant role in cardiorenal and metabolic disease states, including heart failure, atherosclerosis, hypertension.
in vivo	SB-657510 inhibits the progression of high-fat diet induced atherosclerosis and diabetes-associated atherosclerosis^[1]. Levels of phosphorylated ERK are significantly attenuated in the aorta of SB-657510-treated (30 mg/kg/day) diabetic mice (Male Apoe KO mice)^[3].

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Preparation Products And Raw materials

Tag:2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide(474960-44-6) Related Product Information