H-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu-OH manufacturers
|
| | H-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu-OH Basic information |
| | H-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu-OH Chemical Properties |
| density | 1.51±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | pka | 3.37±0.10(Predicted) | | form | Solid | | color | White to off-white | | Sequence | Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | H-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu-OH Usage And Synthesis |
| Uses | Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts[1][2]. | | Biological Activity | Protein Target: PKC', 'Target Sub-Family: AGC | | References | [1] Farrar YJ, et al. A phosphatase resistant substrate for the assay of protein kinase C in crude tissue extracts. Biochem Biophys Res Commun. 1991;180(2):694-701. DOI:10.1016/s0006-291x(05)81121-0 [2] Yasuda I, et al. A synthetic peptide substrate for selective assay of protein kinase C. Biochem Biophys Res Commun. 1990;166(3):1220-1227. DOI:10.1016/0006-291x(90)90996-z |
| | H-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu-OH Preparation Products And Raw materials |
|