| Company Name: |
SPIRO PHARMA |
| Tel: |
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| Email: |
eric_feng1954@126.com |
AVL 292 benzenesulfonate manufacturers
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| | AVL 292 benzenesulfonate Basic information |
| Product Name: | AVL 292 benzenesulfonate | | Synonyms: | AVL 292 benzenesulfonate;AVL-292 (benzenesulfonate);AVL292 benzenesulfonate;Spebrutinib (AVL-292) benzenesulfonate;AVL292 BENZENESULFONATE; AVL 292 BENZENESULFONATE; SPEBRUTINIB BESYLATE; CC-292 BESYLATE;AVL-292 besylate;CC-292 besylate);Spebrutinib besylate (AVL-292 benzenesulfonate | | CAS: | 1360053-81-1 | | MF: | C28H28FN5O6S | | MW: | 581.62 | | EINECS: | | | Product Categories: | | | Mol File: | 1360053-81-1.mol |  |
| | AVL 292 benzenesulfonate Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder |
| | AVL 292 benzenesulfonate Usage And Synthesis |
| Uses | Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a potent inhibitor of Btk kinase activity (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s) in biochemical assays. | | References | [1] Evans EK, et al. Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humans. J Pharmacol Exp Ther. 2013 Aug;346(2):219-28. DOI:10.1124/jpet.113.203489 |
| | AVL 292 benzenesulfonate Preparation Products And Raw materials |
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