| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
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| | Anti-axin 1 Basic information |
| Product Name: | Anti-axin 1 | | Synonyms: | Anti-AXIN1 (C-terminal) antibody produced in goat;Monoclonal Anti-AXIN1 antibody produced in mouse;Anti-axin 1;Anti-MGC52315;Anti-AXIN;axin 1;Anti-Axin1(C-terminal);Anti-Axis inhibition protein 1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti-axin 1 Structure]() |
| | Anti-axin 1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | mouse |
| Storage Class | 10 - Combustible liquids |
| | Anti-axin 1 Usage And Synthesis |
| Uses | This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. (provided by RefSeq) |
| | Anti-axin 1 Preparation Products And Raw materials |
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