| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
Nav1.7-IN-2 manufacturers
- Nav1.7-IN-2
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- $347.00
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2026-04-20
- CAS:1332295-35-8
- Purity:
- Supply Ability: 10g
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| | Nav1.7-IN-2 Basic information |
| Product Name: | Nav1.7-IN-2 | | Synonyms: | Nav1.7-IN-2;Benzamide,3-[[4-[3-(4-fluoro-2-methylphenoxy)-1-azetidinyl]-2-pyrimidinyl]amino]-N-methyl-;3-[[4-[3-(4-fluoro-2-methylphenoxy)-1-azetidinyl]-2-pyrimidinyl]amino]-N-methyl-;Nav1.7 inhibitor 2;Nav-1.7-IN-2,Nav1.7 IN 2,Nav1.7IN2;Carbamazepine-d | | CAS: | 1332295-35-8 | | MF: | C22H22FN5O2 | | MW: | 407.44 | | EINECS: | | | Product Categories: | | | Mol File: | 1332295-35-8.mol |  |
| | Nav1.7-IN-2 Chemical Properties |
| density | 1.318±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 14.90±0.46(Predicted) | | color | White to off-white |
| | Nav1.7-IN-2 Usage And Synthesis |
| Uses | Nav1.7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1.7, with IC50 of 80 nM.
IC50 value: 80 nM
Target: Nav 1.7
Nav1.7-IN-2 is useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorder. The more detailed information please refer to WO 2011103196 A1. Nav1.7-IN-2 is a Nav1.7 channel inhibitor extracted from patent WO/2011103196 A1, compound example J, has an IC50 of 80 nM. | | IC 50 | Nav1.7: 80 nM (IC50) | | References | [1] Bregman Howard, et al. Preparation of aryl carboxamide derivatives as sodium channel inhibitors for treatment of pain. From PCT Int. Appl. (2011), WO 2011103196 A1 20110825. |
| | Nav1.7-IN-2 Preparation Products And Raw materials |
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