1189561-66-7
| 中文名称 | 1189561-66-7 |
|---|---|
| 中文同义词 | BCL-2抑制剂((S)-GOSSYPOL ACETIC ACID);(S)-(+)-GOSSYPOL ACETIC ACID|||(S)-GOSSYPOL ACETIC ACID;化合物 (S)-GOSSYPOL (ACETIC ACID);化合物:(S)-Gossypol acetic acid CAS:1189561-66-7;化合物：(S)-Gossypol acetic acid CAS:1189561-66-7;(S)-棉子酚乙酸 |
| 英文名称 | (S)-Gossypol (acetic acid) |
| 英文同义词 | (S)-Gossypol (acetic acid) |
| CAS号 | 1189561-66-7 |
| 分子式 | C32H34O10 |
| 分子量 | 578.61 |
| EINECS号 | |
| 相关类别 | 细胞生物学试剂 |
| Mol文件 | 1189561-66-7.mol |
| 结构式 |  |
1189561-66-7 性质
| 储存条件 | Store at -20°C, protect from light, stored under nitrogen |
|---|---|
| 溶解度 | DMSO：50mg/mL（86.41mM）；水：< 0.1 mg/mL（不溶） |
| 形态 | 固体 |
| 颜色 | 浅黄至黄色 |
|
Bcl-2
|
Bcl-xL
|
The natural racemic Gossypol has two enantiomers, namely the (-)-Gossypol and (S)-Gossypol ((+)-Gossypol) enantiomers. (+)-Gossypol and (-)-Gossypol binds to Bcl-2 or Bcl-xL with similar binding affinities. (-)-Gossypol is more potent than (+)-Gossypol in inhibition of cell growth and induction of apoptosis. The racemic form and each of the enantiomers of Gossypol are tested against UM-SCC-6 and UM-SCC-14A in 6-day MTT assays. (-)-Gossypol exhibits greater growth inhibition relative to (±)-Gossypol than (+)-Gossypol in both cell lines tested (P<0.001). An intermediate growth inhibitory effect is observed with (±)-Gossypol but this effect is only observed at the higher dose of Gossypol (10 μM, P<0.0001).
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-15464D | (S)-Gossypol (acetic acid) | 1189561-66-7 | 5 mg | 875元 |
| 2026/06/05 | HY-15464D | 1189561-66-7 (S)-Gossypol (acetic acid) | 1189561-66-7 | 10mg | 1254元 |