| Company Name: |
Chembest Research Laboratories Limited
|
| Tel: |
+86-21-20908456 |
| Email: |
sales@BioChemBest.com |
| Products Intro: |
Product Name:(S)-Gossypol acetic acid
CAS:1189561-66-7
Purity:98% HPLC Package:10mg;50mg;100mg;500mg;1g Remarks:Biochemical Reagents; Pharmaceutical Intermediates
|
(S)-Gossypol (acetic acid) manufacturers
|
| | (S)-Gossypol (acetic acid) Basic information |
| | (S)-Gossypol (acetic acid) Chemical Properties |
| storage temp. | Store at -20°C, protect from light, stored under nitrogen | | solubility | DMSO: 50 mg/mL (86.41 mM); Water: < 0.1 mg/mL (insoluble) | | form | Solid | | color | Light yellow to yellow |
| | (S)-Gossypol (acetic acid) Usage And Synthesis |
| Uses | (S)-Gossypol is the isomer of a natural product Gossypol. (S)-Gossypol binds to the BH3-binding groove of Bcl-xL and Bcl-2 proteins with high affinity. | | IC 50 | Bcl-2; Bcl-xL | | References | [1] Oliver CL, et al. In vitro effects of the BH3 mimetic, (-)-Gossypol, on head and neck squamous cell carcinoma cells. Clin Cancer Res. 2004 Nov 15;10(22):7757-63. DOI:10.1158/1078-0432.CCR-04-0551 |
| | (S)-Gossypol (acetic acid) Preparation Products And Raw materials |
| Preparation Products | [2,2'-Binaphthalene]-1,1',6,6',7,7'-hexol, 3,3'-dimethyl-5,5'-bis(1-methylethyl)-, (2R)--->gossypolone |
|