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| | 2-AMINO-5-BROMOBENZAMIDE Basic information |
| Product Name: | 2-AMINO-5-BROMOBENZAMIDE | | Synonyms: | 2-AMINO-5-BROMOBENZAMIDE;2-Amino-5-bromobenzamide ,97%;Benzamide, 2-amino-5-bromo-;5-bromoanthranilamide;5-Methoxy-phthalicacid;Morphinan-3,14-diol,4,5-epoxy-6-(3,6,9,12,15,18,21-heptaoxadocos-1-yloxy)-17-(2-propen-1-yl)-,(5α,6α)-,ethanedioate(1:6)(salt) | | CAS: | 16313-66-9 | | MF: | C7H7BrN2O | | MW: | 215.05 | | EINECS: | 200-589-5 | | Product Categories: | | | Mol File: | 16313-66-9.mol |  |
| | 2-AMINO-5-BROMOBENZAMIDE Chemical Properties |
| Melting point | 189-191℃ (water ethanol ) | | Boiling point | 291.2±25.0℃ (760 Torr) | | density | 1.698±0.06 g/cm3 (20 ºC 760 Torr) | | Fp | 129.9±23.2℃ | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 15.15±0.50(Predicted) | | Appearance | White to off-white Solid |
| | 2-AMINO-5-BROMOBENZAMIDE Usage And Synthesis |
| Chemical Properties | Off-white to light yellow solid | | Synthesis | The general procedure for the synthesis of 2-amino-5-bromobenzamide from benzimidic acid,2-amino- (9CI) was as follows: 2-aminobenzamide (1.00 g, 7.34 mmol) was dissolved in acetonitrile (20 mL) at room temperature and N-bromosuccinimide (1.36 g, 7.70 mmol) was added with stirring. The reaction mixture was stirred continuously at room temperature for 0.5 h. The reaction was subsequently quenched with ice-cold water. The resulting precipitate was collected by filtration and the residue was recrystallized with acetonitrile to afford the light yellow solid product 2-amino-5-bromobenzamide (1.47 g, 93% yield) with a melting point of 186-187 °C (literature value: 185-187 °C, 27 °C). | | References | [1] Tetrahedron, 2016, vol. 72, # 1, p. 123 - 133
[2] Tetrahedron Letters, 2006, vol. 47, # 23, p. 3889 - 3892
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 14, p. 4040 - 4043
[4] Archiv der Pharmazie, 1981, vol. 314, # 2, p. 176 - 180
[5] Molecules, 2017, vol. 22, # 1, |
| | 2-AMINO-5-BROMOBENZAMIDE Preparation Products And Raw materials |
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