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info@bocsci.com |
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PNU-282987 (S enantiomer free base) manufacturers
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| | PNU-282987 (S enantiomer free base) Basic information |
| Product Name: | PNU-282987 (S enantiomer free base) | | Synonyms: | PNU-282987 (S enantiomer free base);Benzamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-;PNU-282987 S-Enantiomer;Inhibitor,Nicotinic acetylcholine receptors,PNU 282987 S enantiomer free base,PNU282987 S enantiomer free base,PNU-282987 S enantiomer,inhibit,nAChR;(S)-4-Chloro-N-(quinuclidin-3-yl)benzamide;PNU-282987 S enantiomer free base, 10 mM in DMSO;PNU-282987 S enantiomer free base ,S0521;PNU-282987 Impurity 2 | | CAS: | 737727-12-7 | | MF: | C14H17ClN2O | | MW: | 264.75 | | EINECS: | | | Product Categories: | | | Mol File: | 737727-12-7.mol |  |
| | PNU-282987 (S enantiomer free base) Chemical Properties |
| Boiling point | 431.5±30.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 13.86±0.20(Predicted) | | color | White to off-white |
| | PNU-282987 (S enantiomer free base) Usage And Synthesis |
| Uses | PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base. PNU-282987 is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist. | | References | [1] Bodnar AL, et al. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. J Med Chem. 2005 Feb 24;48(4):905-8. DOI:10.1021/jm049363q |
| | PNU-282987 (S enantiomer free base) Preparation Products And Raw materials |
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