2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine

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2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine manufacturers
2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine Basic information
Product Name:2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine
Synonyms:2-Amino-6-chloropurine-9-beta-D-(2'-deoxy)riboside;2-AMINO-6-CHLOROPURINE-2'-DEOXYRIBOSIDE;2-AMINO-6-CHLOROPURINE-2'-DEOXY-D-RIBOFURANOSIDE;2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine;(2R,3S,5S)-5-(2-AMino-6-chloro-9H-purin-9-yl)-2-(hydroxyMethyl)tetrahydrofuran-3-ol;2-Amino-6-chloro-9-(β-D-2-deoxyribofuranosyl)purine;9H-Purin-2-amine, 6-chloro-9-(2-deoxy-β-D-erythro-pentofuranosyl)-;2-Amino-6-chloro-9-(β-D-2-deoxyribofuranosyl) purine
CAS:120595-72-4
MF:C10H12ClN5O3
MW:285.69
EINECS:
Product Categories:
Mol File:120595-72-4.mol
2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine Structure
2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine Chemical Properties
Melting point 120 °C (decomp)
Boiling point 681.909±65.00 °C(Press: 760.00 Torr)(predicted)
density 2.038±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. 2-8°C
pka13.749±0.60(predicted)
InChIInChI=1/C10H12ClN5O3/c11-8-7-9(15-10(12)14-8)16(3-13-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,14,15)/t4-,5+,6+/s3
InChIKeyLEDIVMUMDVEFRG-FLEGHBDQNA-N
SMILESN1(C=NC2C(Cl)=NC(N)=NC1=2)[C@H]1C[C@H](O)[C@@H](CO)O1 |&1:11,13,15,r|
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MSDS Information
2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine Usage And Synthesis
Uses2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine Preparation Products And Raw materials
Tag:2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine(120595-72-4) Related Product Information
2-Amino-6-chloro-9-(3,5-di-O-(p-toluoyl)-beta-D-2-deoxyribofurnanosyl)purine 2-Amino-6-chloro-9-(beta-D-arabinofuranosyl)-9H-purine 2-Amino-6-chloropurine-2'-deoxyriboside-5'-triphosphate lithium salt 2-Acetamido-9-(2,3,5-tri-O-benzyl-beta-D-arabinofuranosyl)-6-chloro-9H-purine 2-Amino-6-chloropurineriboside-5'-triphosphate lithium salt 2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-beta-D-ribofuranosyl)purine 2-Amino-6-chloro-9-(beta-D-2-deoxyribofuranosyl)purine 6-Chloropurine-2'-deoxyriboside 2-Amino-6-chloropurine Riboside 6-Chloropurine 2',3',5'-Tri-O-acetyl-2-aMino-6-chloropurine Riboside TIMTEC-BB SBB002967