N-(Propargyl-PEG2)-N-bis(PEG1-alcohol)

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N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) Basic information
Product Name:N-(Propargyl-PEG2)-N-bis(PEG1-alcohol)
Synonyms:N-(Propargyl-PEG2)-N-bis(PEG1-alcohol);Propargyl-PEG2-N-bis(PEG2);3,9,12-Trioxa-6-azapentadec-14-yn-1-ol, 6-[2-(2-hydroxyethoxy)ethyl]-
CAS:2100306-62-3
MF:C15H29NO6
MW:319.39
EINECS:
Product Categories:
Mol File:2100306-62-3.mol
N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) Structure
N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) Chemical Properties
Boiling point 440.2±40.0 °C(Predicted)
density 1+-.0.06 g/cm3(Predicted)
solubility Soluble in Water, DMSO, DCM, DMF
pka14.10±0.10(Predicted)
Safety Information
MSDS Information
N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) Usage And Synthesis
DescriptionN-(Propargyl-PEG2)-N-bis(PEG1-alcohol) is a multi-arm linker that can form triazole linkage with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry.
UsesPropargyl-PEG2-N-bis(PEG2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-N-bis(PEG2) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) Preparation Products And Raw materials
Tag:N-(Propargyl-PEG2)-N-bis(PEG1-alcohol)(2100306-62-3) Related Product Information
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