4-甲基伞形酮磷酸酯
| 中文名称 | 4-甲基伞形酮磷酸酯 |
|---|---|
| 中文同义词 | MUP无游离酸[4-甲基伞形酮磷酸酯];4-甲基伞形酮磷酸酯 4-METHYLUMBELLIFERYL PHOSPHATE;磷酸 4-甲基伞形酮酯;4-甲基香豆素基磷酸酯;4-甲基伞形酮磷酸酯(磷酸4-甲基伞形酮酯);4-甲基-2-氧代-2H-1-苯并吡喃-7-基磷酸酯;4-甲基伞形酮酰磷酸酯;4-甲基伞形酮磷酸酯 |
| 英文名称 | 4-METHYLUMBELLIFERYL PHOSPHATE |
| 英文同义词 | (4-MUP) LIQUID SUBSTRATE SYSTEM;4-MUP;4-METHYLUMBELLIFERONE PHOSPHATE;4-METHYLUMBELLIFERYL PHOSPHATE;4-METHYLUMBELLIFERYL-PHOSPHORIC ACID;4-METHYLUMBELLIFERYL PHOSPHATE LIQUID SUBSTRATE SYSTEM;4-METHYL-7-(PHOSPHONOOXY), 2H-1-BENZOPYRAN-2-ONE;4-METHYL-2-OXO-2H-CHROMEN-7-YL DIHYDROGEN PHOSPHATE |
| CAS号 | 3368-04-5 |
| 分子式 | C10H9O6P |
| 分子量 | 256.15 |
| EINECS号 | 222-137-7 |
| 相关类别 | 生化试剂;酶与辅酶 |
| Mol文件 | 3368-04-5.mol |
| 结构式 |  |
4-甲基伞形酮磷酸酯 性质
| 熔点 | 215-218 °C |
|---|---|
| 沸点 | 511.4±60.0 °C(Predicted) |
| 密度 | 1.583±0.06 g/cm3(Predicted) |
| 储存条件 | -20°C |
| 溶解度 | DMF：10mg/mL； DMSO：20mg/mL； PBS（pH 7.2）：5 mg/mL |
| 酸度系数(pKa) | 1.65±0.10(Predicted) |
| 形态 | 液体 |
| 颜色 | 白色至类白色 |
| PH值 | pH (5g/l, 25℃) : 1.5～2.3 |
| 水溶解性 | Soluble in water |
| BRN | 1687229 |
| InChI | InChI=1S/C10H9O6P/c1-6-4-10(11)15-9-5-7(2-3-8(6)9)16-17(12,13)14/h2-5H,1H3,(H2,12,13,14) |
| InChIKey | BCHIXGBGRHLSBE-UHFFFAOYSA-N |
| SMILES | C1(=O)OC2=CC(OP(O)(O)=O)=CC=C2C(C)=C1 |
| CAS 数据库 | 3368-04-5(CAS DataBase Reference) |
| EPA化学物质信息 | 2H-1-Benzopyran-2-one, 4-methyl-7-(phosphonooxy)- (3368-04-5) |
4-Methylumbelliferyl phosphate (4-MUP) 是一种碱性磷酸酶的荧光底物。
4-Methylumbelliferyl phosphate monoester previously described as one of a series of 4-methylumbelliferone conjugates is later found to be the PlP2-pyrophosphate diester and is not hydrolysed by serum phosphomonoesterases . 4-Methylumbelliferyl phosphate has a significant advantage over currently available substrates in that its useful concentration range extends to about 0.1 μM.
If the concentration of 4-Methylumbelliferyl phosphate is held constant and the pH is varied, the activity of the enzyme passes through a maximum.
安全信息
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