4-Boc-amino-2,2-dimethylbutyric acid

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4-Boc-amino-2,2-dimethylbutyric acid Basic information
Product Name:4-Boc-amino-2,2-dimethylbutyric acid
Synonyms:4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2,2-Dimethyl-Butanoic Acid;4-((tert-Butoxycarbonyl)amino)-2,2-dimethylbutanoic acid;CAS_153039-17-9;Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-2,2-dimethyl-;4-(Boc-amino)-2,2-dimethyl-butanoic acid;4-BOC-AMINO-2,2-DIMETHYLBUTYRIC ACID ISO 9001:2015 REACH;4-Boc-amino-2,2-dimethylbutyric acid
CAS:153039-17-9
MF:C11H21NO4
MW:231.29
EINECS:
Product Categories:pharmacetical
Mol File:153039-17-9.mol
4-Boc-amino-2,2-dimethylbutyric acid Structure
4-Boc-amino-2,2-dimethylbutyric acid Chemical Properties
Boiling point 369.9±25.0 °C(Predicted)
density 1.065±0.06 g/cm3(Predicted)
pka4.81±0.10(Predicted)
Safety Information
MSDS Information
4-Boc-amino-2,2-dimethylbutyric acid Usage And Synthesis
Uses4-Boc-amino-22-dimethylbutyric acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
4-Boc-amino-2,2-dimethylbutyric acid Preparation Products And Raw materials
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