MC-Sq-Cit-PAB-Dolastatin10

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MC-Sq-Cit-PAB-Dolastatin10 Suppliers list
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
MC-Sq-Cit-PAB-Dolastatin10 Basic information
Product Name:MC-Sq-Cit-PAB-Dolastatin10
Synonyms:MC-Sq-Cit-PAB-Dolastatin10
CAS:1941168-65-5
MF:C70H105N12O12S+
MW:1338.72
EINECS:
Product Categories:
Mol File:1941168-65-5.mol
MC-Sq-Cit-PAB-Dolastatin10 Structure
MC-Sq-Cit-PAB-Dolastatin10 Chemical Properties
pka11.132±0.46(predicted)
Safety Information
MSDS Information
MC-Sq-Cit-PAB-Dolastatin10 Usage And Synthesis
UsesMC-Sq-Cit-PAB-Dolastatin10 is a agent-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.
IC 50Auristatin
References[1] FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1.
[2] Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119. DOI:10.1038/nchem.2635
MC-Sq-Cit-PAB-Dolastatin10 Preparation Products And Raw materials
Tag:MC-Sq-Cit-PAB-Dolastatin10(1941168-65-5) Related Product Information
Pelidotin MC-Sq-Cit-PAB-Dolastatin10 MonoMethyl Dolastatin 10 PF-06380101 McMMAD AcLys-PABC-VC-Aur0101