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| | N,N-Diethylethylenediamine Basic information |
| | N,N-Diethylethylenediamine Chemical Properties |
| Melting point | <-70°C | | Boiling point | 145-147 °C(lit.) | | density | 0.827 g/mL at 25 °C(lit.) | | vapor pressure | 5.33hPa at 20℃ | | refractive index | n20/D 1.436(lit.) | | Fp | 87 °F | | storage temp. | Store below +30°C. | | solubility | soluble in Methanol, Water | | form | Liquid | | pka | pK1:7.70(+2);pK2:10.46(+1) (25°C) | | color | Clear colorless to light yellow | | explosive limit | 0.7-8.4%(V) | | Water Solubility | MISCIBLE | | Sensitive | Air Sensitive | | BRN | 605299 | | InChI | 1S/C6H16N2/c1-3-8(4-2)6-5-7/h3-7H2,1-2H3 | | InChIKey | PQZTVWVYCLIIJY-UHFFFAOYSA-N | | SMILES | CCN(CC)CCN | | LogP | 0.1 at 25℃ | | CAS DataBase Reference | 100-36-7(CAS DataBase Reference) | | NIST Chemistry Reference | 1,2-Ethanediamine, N,N-diethyl-(100-36-7) | | EPA Substance Registry System | N,N-Diethylethylenediamine (100-36-7) |
| Hazard Codes | C,Xi | | Risk Statements | 10-20/21/22-35-21-36/37/38-34 | | Safety Statements | 26-36/37/39-45-25-16-36-27 | | RIDADR | UN 2685 8/PG 2 | | WGK Germany | 1 | | RTECS | KV3500000 | | Autoignition Temperature | 245 °C | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29212900 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 3 Dermal
Acute Tox. 4 Inhalation
Flam. Liq. 3
Skin Corr. 1A | | Toxicity | LD50 orally in Rabbit: 984 mg/kg LD50 dermal Rabbit 820 mg/kg |
| | N,N-Diethylethylenediamine Usage And Synthesis |
| Chemical Properties | CLEAR COLORLESS TO LIGHT YELLOW LIQUID | | Uses | N,N-Diethylethylenediamine is used in the syntheses of anti-malarials. In addition, it has been seem to induce apoptosis through a caspase-3 dependent pathway. | | Uses | N,N-Diethylethylenediamine was used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides. It is also used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma. | | Flammability and Explosibility | Flammable | | Safety Profile | Poison by
intraperitoneal route. Moderately toxic by
ingestion and skin contact. A slun and
severe eye irritant. Flammable liquid when
exposed to heat or flame; can react with
oxidzing materials. To fight fire, use alcohol
foam, CO2, dry chemical. When heated to
decomposition it emits toxic fumes of NOx.
See also AMINES. | | Toxics Screening Level | The initital threshold screening level (ITSL) for 2-diethylaminoethylamine is 9 μg/m3 based on an annual averaging time. |
| | N,N-Diethylethylenediamine Preparation Products And Raw materials |
| Raw materials | Acrylonitrile-->AMINOACETONITRILE | | Preparation Products | softener BCH-->sapamine CH-->2-Aminoethyl(ethyl)amine-->etonitazene-->CAMYLOFINE DIHYDROCHLORIDE-->Tiapride-->N-T-BOC-PYRROLE-->Butonitazene-->1,2-Ethanediamine, N2-cyclohexyl-N1,N1-diethyl--->1,4-Naphthalenedione, 2-chloro-3-[[2-(diethylamino)ethyl]amino]--->N-[(4-chlorophenyl)methyl]-N',N'-diethylethane-1,2-diamine-->N-[2-(Diethylamino)ethyl]-4-chlorobenzamide-->N,N-Bis(2-mercaptoethyl)-N'',N''-diethylethylenediamine-->3-Chloro-N-[2-(diethylaMino)ethyl]benzaMide, 97%-->Metonitazene-->N-[2-(Diethylamino)ethyl]-4-methoxybenzamide, 97% |
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