3,7-二氢-1-甲基-1H-嘌呤-2,6-二酮
| 中文名称 | 3,7-二氢-1-甲基-1H-嘌呤-2,6-二酮 |
|---|---|
| 中文同义词 | 1-甲基黄嘌呤;3,7-二氢-1-甲基-1H-嘌呤-2,6-二酮;甲基黄嘌呤;6-二羟基-1-甲基嘌呤;2,6-二羟基-1-甲基嘌呤;1-甲基化黄嘌呤衍生物;聽1-METHYLXANTHINE;己酮可可碱21 |
| 英文名称 | 1-Methylxanthine |
| 英文同义词 | 1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-;1-Methyl-3,7-dihydro-1H-purine-2,6-dione;1-methyl-xanthin;Xanthine, 1-methyl-;3,7-dihydro-1-methyl-1H-purine-2,6-dione;2,6-DIHYDROXY-1-METHYLPURINE;1-Methyl-7H-purine-2,6(1H,3H)-dione;1-methyl-3,4,5,7-tetrahydro-1H-purine-2,6-dione/1-Methylxanthine |
| CAS号 | 6136-37-4 |
| 分子式 | C6H6N4O2 |
| 分子量 | 166.14 |
| EINECS号 | 228-108-5 |
| 相关类别 | 医药中间体，医药原料，精细化工品。;有机砌块;医药中间体;杂环砌块;其他化学试剂;Heterocycles;Metabolites & Impurities;Bioactive Small Molecules;Building Blocks;Cell Biology;Chemical Synthesis;Heterocyclic Building Blocks;M;Isolabel;嘌呤;Various Metabolites and Impurities;Bases & Related Reagents;Metabolites;Nucleotides;Purines |
| Mol文件 | 6136-37-4.mol |
| 结构式 |  |
3,7-二氢-1-甲基-1H-嘌呤-2,6-二酮 性质
| 熔点 | ≥300 °C |
|---|---|
| 密度 | 1.539±0.06 g/cm3(Predicted) |
| 储存条件 | Sealed in dry,Room Temperature |
| 溶解度 | 碱性溶液（微溶），DMSO（微溶） |
| 形态 | 固体 |
| 酸度系数(pKa) | pK1:7.70;pK2:12.0 (25°C) |
| 颜色 | 浅黄色至深黄色 |
| 最大波长(λmax) | 270nm(H2O)(lit.) |
| BRN | 171507 |
| InChI | InChI=1S/C6H6N4O2/c1-10-5(11)3-4(8-2-7-3)9-6(10)12/h2H,1H3,(H,7,8)(H,9,12) |
| InChIKey | MVOYJPOZRLFTCP-UHFFFAOYSA-N |
| SMILES | N1C2=C(NC(=O)N(C)C2=O)NC=1 |
| CAS 数据库 | 6136-37-4(CAS DataBase Reference) |
1-Methylxanthine 是一种咖啡因衍生物，是咖啡因和茶碱 (1,3-二甲基黄嘌呤，TP) 在人体尿代谢产物。1-Methylxanthine 可增强肿瘤细胞的放射敏感性。
|
Human Endogenous Metabolite
|
1-Methylxanthine (1-MTX; 3 mM; for 30 min) increases the radiation-induced clonogenic and apoptotic cell (RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53)) death.
1-Methylxanthine (1MX) exhibits similar activities to other naturally occurring methylxanthines. Unlike caffeine, TP, and theobromine, 3-Methylxanthine (3MX) and 1-methylxanthine do not occur naturally at high levels in plants.
| 提供商 | 语言 |
|---|---|
|
英文
|