1-Propanol, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- (9CI) manufacturers
- OH-Pr-PEG2-Pr-OH
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2025-06-07
- CAS:112935-57-6
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | 1-Propanol, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- (9CI) Basic information |
| Product Name: | 1-Propanol, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- (9CI) | | Synonyms: | 1-Propanol, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- (9CI);HO-PPG1-PEG2-PPG1-OH;Propanol-PEG3-CH2OH;OH-Pr-PEG2-Pr-OH;HO-PPG1-PEG2-PPG1-OH/3,3'-[Oxybis(ethanediyloxy)]di(1-propanol);3-[2-[2-(3-hydroxypropoxy)ethoxy]ethoxy]propan-1-ol;HO-(CH2)3-PEG2-O-(CH2)3-OH | | CAS: | 112935-57-6 | | MF: | C10H22O5 | | MW: | 222.28 | | EINECS: | | | Product Categories: | | | Mol File: | 112935-57-6.mol | ![1-Propanol, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- (9CI) Structure](CAS/20210111/GIF/112935-57-6.gif) |
| | 1-Propanol, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- (9CI) Chemical Properties |
| Boiling point | 351.4±27.0 °C(Predicted) | | density | 1.070±0.06 g/cm3(Predicted) | | pka | 14.57±0.10(Predicted) |
| | 1-Propanol, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- (9CI) Usage And Synthesis |
| Uses | Propanol-PEG3-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | Propanol-PEG3-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | 1-Propanol, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- (9CI) Preparation Products And Raw materials |
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