1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]-

Request For Quotation
1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Company Name: Beijing Boorsen Biotechnology Co., Ltd  
Tel: 400-901-9800 18611424007
Email: cis@bioss.com.cn
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology  
Tel: 18143011203
Email: ET-market@chemextension.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn

1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]- manufacturers

  • CPS-11
  • CPS-11 pictures
  • $228.00
  • 2026-09-10
  • CAS:145945-21-7
  • Purity: 99.80%
  • Supply Ability: 10g
1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]- Basic information
Product Name:1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]-
Synonyms:1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]-;CPS 11;CPS11;CPS-11
CAS:145945-21-7
MF:C14H12N2O5
MW:288.26
EINECS:
Product Categories:
Mol File:145945-21-7.mol
1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]- Structure
1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]- Chemical Properties
Boiling point 561.5±45.0 °C(Predicted)
density 1.555±0.06 g/cm3(Predicted)
form Solid
pka13.37±0.10(Predicted)
color White to off-white
Safety Information
MSDS Information
1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]- Usage And Synthesis
UsesCPS-11 (N-(Hydroxymethyl)thalidomide) a Thalidomide (HY-14658) analogue, is a potent anti-cancer agent. CPS-11 inhibits NF-κB, activates NFAT, and repress cytokine expression through elevated ROS. CPS-11 exhibits a wider activity spectrum and higher potency against MM (multiple myeloma) cell lines[1][2][3].
References[1] Aragon-Ching JB, et al. Thalidomide analogues as anticancer drugs. Recent Pat Anticancer Drug Discov. 2007 Jun;2(2):167-74. DOI:10.2174/157489207780832478
[2] Warfel NA, et al. Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3502-9. DOI:10.1158/1078-0432.CCR-05-1837
[3] Ge Y, et al. Selective leukemic-cell killing by a novel functional class of thalidomide analogs. Blood. 2006 Dec 15;108(13):4126-35. DOI:10.1182/blood-2006-04-017046
1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]- Preparation Products And Raw materials
Tag:1H-Isoindole-1,3(2H)-dione, 2-[1-(hydroxymethyl)-2,6-dioxo-3-piperidinyl]-(145945-21-7) Related Product Information
Uridine Sodium dichloroacetate Y-27632 Dimethyl 2-oxoglutarate 5-Aminosalicylic acid N-Acetyl-L-cysteine