5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester

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Company Name: Shanghai EFE Biological Technology Co., Ltd.  
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Company Name: TargetMol Chemicals Inc.  
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5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester manufacturers

  • MS438
  • MS438 pictures
  • $2180.00
  • 2026-07-27
  • CAS:512840-45-8
  • Purity:
  • Supply Ability: 10g
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester Basic information
Product Name:5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester
Synonyms:5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester;MS438;Benzyl6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS:512840-45-8
MF:C20H17F3N2O3
MW:390.36
EINECS:
Product Categories:
Mol File:512840-45-8.mol
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester Structure
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester Chemical Properties
Boiling point 481.6±45.0 °C(Predicted)
density 1.299±0.06 g/cm3(Predicted)
pka10.85±0.70(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester Usage And Synthesis
DescriptionMS438 is a potent agonist of the TSH receptor (TSHR).
UsesMS438 is a potent thyrotropin receptor (TSHR) agonist with an EC50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice[1].
References[1] Latif R, et al. New small molecule agonists to the thyrotropin receptor. Thyroid. 2015 Jan;25(1):51-62. DOI:10.1089/thy.2014.0119
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester Preparation Products And Raw materials
Tag:5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester(512840-45-8) Related Product Information
Ethyl 4-(4-isopropylphenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate methyl 4-(4-(benzyloxy)phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate benzyl 4-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate ethyl 4-(4-hydroxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-, phenylmethyl ester 1,2,3,4-Tetrahydro-6-methyl-2-oxo-4-[2-(trifluoromethyl)phenyl]-5-pyrimidinecarb