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- avermectin B1b
-
- $1.00
-
2020-02-14
- CAS:65195-56-4
- Min. Order: 1KG
- Purity: Min98% HPLC
|
| | Avermectin B1b Basic information |
| Product Name: | Avermectin B1b | | Synonyms: | avermectin b1b;Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-;5-O-Demethyl-25-de(1-methylpropyl)-25-isopropylAvermectin A1a;Antibiotic C-076B1b;C-076B1b;AbaMectin B1b;Ivermectin Impurity 2(Ivermectin EP Impurity B);Abamectin B1b (~90%) | | CAS: | 65195-56-4 | | MF: | C47H70O14 | | MW: | 859.05 | | EINECS: | 265-611-9 | | Product Categories: | | | Mol File: | 65195-56-4.mol |  |
| | Avermectin B1b Chemical Properties |
| Boiling point | 934.6±65.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | solid | | pka | 12.42±0.70(Predicted) | | color | white | | Stability: | Unstable in Solution, Very Hygroscopic | | InChIKey | ZFUKERYTFURFGA-VMROQZAPNA-N | | EPA Substance Registry System | Avermectin B1b (65195-56-4) |
| RIDADR | 2588 | | HazardClass | 6.1(a) | | PackingGroup | II |
| | Avermectin B1b Usage And Synthesis |
| Uses | Avermectin B1b is the minor component (<20%) of a commercially available anthelmintic used to control parasitic nematodes in livestock. Avermectin B1b contains a isopropyl residue in the 25-position. In vitro and in vivo studies have shown this analogue to be active, but less potent than the B1a analogue | | Definition | ChEBI: Avermectin B1b is an avermectin. | | Brand name | (Merck)Avomec [Veterinary] (Merial); Bovitin
[Veterinary] (Merial); Doratect [Veterinary] (Merial);
Duomectin [Veterinary] (Merial); Duotin [Veterinary]
(Merial); Endecto (Merck); Enzec (Merck); Enzek
(Merck); Parafoil (Merck); Vertimil (Zectin
(Merck). | | Biological Activity | avermectin b1 is a mixture of avermectins containing >80% avermectin b1a and <20% avermectin b1b. b1a and b1b have very similar biological and toxicological properties. | | in vitro | the avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium. avermectin b1 is a natural fermentation product of this bacterium. | | in vivo | avermectin b1 therapy resulted in significant decreases in mean strongyle egg after treatment. all horses given ivermectin or avermectin b1 had zero strongyle egg counts 14 and 28 d after treatment. the oral administration of avermectin b1 appeared to be highly efficacious against intestinal strongyles and onchocera microfilaria [1]. | | references | [1] mogg td, pollitt cc, willmore jp, thompson h. efficacy of avermectin b1 given orally against equine intestinal strongyles and onchocera microfilaria. aust vet j. 1990;67(11):399-401. |
| | Avermectin B1b Preparation Products And Raw materials |
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