- Tipepidine
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- $1520.00
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2026-05-11
- CAS:5169-78-8
- Purity:
- Supply Ability: 10g
- tipepidine USP/EP/BP
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- $1.10
-
2025-11-18
- CAS:5169-78-8
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100Tons min
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| | tipepidine Basic information |
| Product Name: | tipepidine | | Synonyms: | 1-Methyl-3-piperidylidenedi(2-thienyl)methane;3-(Di-2-thienylmethylene)-1-methyl-piperidine;At 327;Bitiodin;Brn 0212554;Cr/662;3-(Dithien-2-ylmethylene)-1-methylpiperidine;3-(dithiophen-2-ylmethylidene)-1-methylpiperidine | | CAS: | 5169-78-8 | | MF: | C15H17NS2 | | MW: | 275.43 | | EINECS: | | | Product Categories: | | | Mol File: | 5169-78-8.mol |  |
| | tipepidine Chemical Properties |
| Melting point | 64-65° | | Boiling point | bp4-5 178-184° | | density | 1.1947 (rough estimate) | | refractive index | 1.5300 (estimate) | | pka | 8.23±0.20(Predicted) | | form | Solid | | color | White to light yellow |
| Toxicity | LD50 in mice (mg/kg): 294 i.p.; 308 i.m.; 867 orally (Higaki) |
| | tipepidine Usage And Synthesis |
| Originator | Sotal,G. Ramon | | Definition | ChEBI: Tipepidine is a member of piperidines. | | Manufacturing Process | From ethyl 1-methylpiperidine-3-carboxylate (which was prepared by
hydrogenation of ethyl nicotinate with Ni-catalyst and then by methylation by
action dimethyl sulfate) and 2-thienyl magnesium bromide was synthesized
1,1-di(thiophen-2-yl)-2-(3'-N-methylpiperidine), 3-(di-2-thienylmethylene)-1-
methylpiperidine was obtained by dehydration of 1,1-di(thiophen-2-yl)-2-(3'-
N-methylpiperidine) by action of base. | | Therapeutic Function | Antitussive, Expectorant |
| | tipepidine Preparation Products And Raw materials |
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