Antitussives

Cough can help clear, sputum and other pathological products in the respiratory tract foreign matter to maintain airway patency, can be seen as a defensive reflex. But severe and frequent cough discomforts the patients, hinder their sleep and rest, also brings about many kinds of concurrent disease. It is necessary to ease the cough with antitussives. Anti-infective drugs are the best antitussive if the infection and inflammation are the cause of cough. In addition, relieving bronchial spasm and eliminating phlegm can also relieve cough to a certain extent. Antitussive medicine act through the inhibition of medulla cough center or act on the periphery, so as to inhibit the arc sensor, afferent nerve, efferent nerve of cough reflex and respiratory tract smooth muscle, etc., to prevent cough reflex and hence achieve antibechic effect. Antitussive drugs can be divided into central and peripheral antitussive drugs. Those can inhibit medulla cough center are known as central antitussive drugs such as codeine, hydroxymethorphol, cloperastine, cough maven, germa crone, etc. Some of them are addictive. Those inhibits other parts of the reflex arc (afferent side, outgoing side) are known as peripheral antitussives such as benzonatate, Narcotine. The main function of these drugs are local anesthesia or protection of the pharynx mucosa from stimulation.
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Structure Chemical Name CAS MF
Erdosteine Erdosteine 84611-23-4 C8H11NO4S2
Quercetin Quercetin 117-39-5 C15H10O7
Quercetin dihydrate Quercetin dihydrate 6151-25-3 C15H14O9
Luteolin Luteolin 491-70-3 C15H10O6
2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE 511-13-7 C17H21Cl2NO
Bengenin Bengenin 477-90-7 C14H16O9
DL-Methylephedrine hydrochloride DL-Methylephedrine hydrochloride 18760-80-0 C11H17NO.ClH
oxolamine dihydrogen phosphate oxolamine dihydrogen phosphate 1949-19-5 C14H22N3O5P
Glaucine HBr Glaucine HBr 5996-06-5 C21H26BrNO4
Droxypropine Droxypropine 15599-26-5 C18H27NO3
Nepinalone Nepinalone 22443-11-4 C18H25NO
morclofone morclofone 31848-01-8 C21H24ClNO5
zipeprol zipeprol 34758-83-3 C23H32N2O3
guaiapate guaiapate 852-42-6 C18H29NO4
TIPEPIDINE HIBENZATE TIPEPIDINE HIBENZATE 31139-87-4 C29H27NO4S2
HYDROCODONE HYDROCODONE 125-29-1 C18H21NO3
HYDROCODONE BITARTRATE HYDROCODONE BITARTRATE 34195-34-1 C22H27NO9
Dimethoxanate hydrochloride Dimethoxanate hydrochloride 518-63-8 C19H22N2O3S.ClH
Pentoxyverine Pentoxyverine 77-23-6 C20H31NO3
PRUNUS SEROTINA (WILD CHERRY) BARK EXTRACT PRUNUS SEROTINA (WILD CHERRY) BARK EXTRACT 8000-44-0
CARBETAPENTANE CITRATE CARBETAPENTANE CITRATE 23142-01-0 C26H39NO10
Pentoxyverine hydrochloride Pentoxyverine hydrochloride 1045-21-2 C20H31NO3.ClH
PHOLCODINE PHOLCODINE 509-67-1 C23H30N2O4
1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]piperidine, monohydrochloride 1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]piperidine, monohydrochloride 982-43-4 C9H13ClN2O
dimemorfan dimemorfan 36309-01-0 C18H25N
(3-cyano-2-methyl-3-phenylhexane-5-yl)dimethylammonium dihydrogen (2-hydroxypropane-1,2,3-tricarboxylate) (3-cyano-2-methyl-3-phenylhexane-5-yl)dimethylammonium dihydrogen (2-hydroxypropane-1,2,3-tricarboxylate) 28416-66-2 C22H32N2O7
Dibunate sodium Dibunate sodium 14992-59-7 C18H23NaO3S
CODEINE CODEINE 76-57-3 C18H21NO3
Tipepidine citrate Tipepidine citrate 14698-07-8 C21H25NO7S2
(5alpha)-6,7-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-yl acetate hydrochloride (5alpha)-6,7-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-yl acetate hydrochloride 20236-82-2 C20H24ClNO4
Drotebanol Drotebanol 3176-03-2 C19H27NO4
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)-, phosphate (1:1) (salt), mixt. with γ-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine (2Z)-2-butenedioate (1:1) (9CI) Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)-, phosphate (1:1) (salt), mixt. with γ-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine (2Z)-2-butenedioate (1:1) (9CI) 60540-98-9 C38H47ClN3O11P
6,8-DIMETHYL-4',5,7-TRIHYDROXYFLAVANONE 6,8-DIMETHYL-4',5,7-TRIHYDROXYFLAVANONE 24211-30-1 C17H16O5
Morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl-, (5α)-, mixt. with γ-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine Morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl-, (5α)-, mixt. with γ-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine 131219-97-1 C34H40ClN3O3
Prenoxdiazine Prenoxdiazine 47543-65-7 C23H27N3O
Alloclamide hydrochloride Alloclamide hydrochloride 5107-01-7 C16H23ClN2O2.ClH
Suxemerid sulfate Suxemerid sulfate 34144-82-6 C24H44N2O4.2H2O4S
Oxolamine Oxolamine 959-14-8 C14H19N3O
(5alpha,6alpha)-4,5-epoxy-3-methoxy-17-methylmorphinan-6-yl acetate hydrochloride (5alpha,6alpha)-4,5-epoxy-3-methoxy-17-methylmorphinan-6-yl acetate hydrochloride 84824-86-2 C20H26ClNO4
butopiprine butopiprine 55837-15-5 C19H29NO3
fedrilate fedrilate 23271-74-1 C20H29NO4
Dextromethorphan hydrobromide monohydrate Dextromethorphan hydrobromide monohydrate 6700-34-1 C18H28BrNO2
HYDROCODONE HYDROCHLORIDE HYDROCODONE HYDROCHLORIDE 25968-91-6 C18H22ClNO3
Benproperine phosphate Benproperine phosphate 19428-14-9 C21H30NO5P
LEVOPROPOXYPHENE NAPSYLATE (300 MG) LEVOPROPOXYPHENE NAPSYLATE (300 MG) 55557-30-7 C19H25NO
nicocodine nicocodine 3688-66-2 C24H24N2O4
Meprotixol Meprotixol 4295-63-0 C19H23NO2S
Dextrorphan hydrochloride Dextrorphan hydrochloride 69376-27-8 C17H24ClNO
Hycodan Hycodan 8013-91-0 C39H51BrN2O12
Morphinan-6α-ol, 4,5α-epoxy-3-methoxy-17-methyl-, phosphate (1:1) (salt) (8CI) Morphinan-6α-ol, 4,5α-epoxy-3-methoxy-17-methyl-, phosphate (1:1) (salt) (8CI) 24204-13-5 C18H26NO7P
Pemerid nitrate Pemerid nitrate 34114-01-7 C15H34N4O7
bibenzonium bromide bibenzonium bromide 15585-70-3 C19H26NO.Br
codoxime codoxime 7125-76-0 C20H24N2O5
N-[3-chloro-2-[[methyl[2-morpholino-2-oxoethyl]amino]methyl]phenyl]benzamide monohydrochloride N-[3-chloro-2-[[methyl[2-morpholino-2-oxoethyl]amino]methyl]phenyl]benzamide monohydrochloride 24600-36-0 C21H25Cl2N3O3
Benzonatate Benzonatate 104-31-4 C30H53NO11
Clobutinol Clobutinol 14860-49-2 C14H22ClNO
clofedanol clofedanol 791-35-5 C17H20ClNO
SAVOURY RHODODENDRON OIL SAVOURY RHODODENDRON OIL
Dextromethorphan Dextromethorphan 125-71-3 C18H25NO
oxeladin oxeladin 468-61-1 C20H33NO3
tipepidine tipepidine 5169-78-8 C15H17NS2
Eprazinone Eprazinone 10402-90-1 C24H32N2O2
Fominoben Fominoben 18053-31-1 C21H24ClN3O3
Picoperine Picoperine
Pemerid Pemerid
isoaminile isoaminile 77-51-0 C16H24N2
NOSCAPINE HYDROCHLORIDE NOSCAPINE HYDROCHLORIDE 912-60-7 C22H24ClNO7
BENPROPERINE BENPROPERINE 2156-27-6 C21H27NO
PRENOXDIAZINE PRENOXDIAZINE C9H12N2O
Dimethoxanate hydrocholoride Dimethoxanate hydrocholoride
9-Chloro-2-methyl-5H-pyrazolo[1,5-d][1,4]benzodiazepin-6(7H)-one 9-Chloro-2-methyl-5H-pyrazolo[1,5-d][1,4]benzodiazepin-6(7H)-one 84661-23-4 C12H10ClN3O
Butamyrate Butamyrate 18109-80-3 C18H29NO3
levopropoxyphene levopropoxyphene 2338-37-6 C22H29NO2
promolate promolate 3615-74-5 C16H23NO4
D-PINITOL D-PINITOL 484-68-4 C7H14O6
RORIFONE RORIFONE C11H23NO3S
caramiphen caramiphen 77-22-5 C18H27NO2
Dimethoxanate Dimethoxanate 477-93-0 C19H22N2O3S
Butamirate citrate Butamirate citrate 18109-81-4 C24H37NO10
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