2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)-

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2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)- manufacturers

  • KRP-199
  • KRP-199 pictures
  • $1670.00
  • 2026-05-11
  • CAS:221164-28-9
  • Purity:
  • Supply Ability: 10g
2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)- Basic information
Product Name:2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)-
Synonyms:2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)-;KRP-199;KRP199,KRP 199
CAS:221164-28-9
MF:C22H14F3N5O7
MW:517.37
EINECS:
Product Categories:
Mol File:221164-28-9.mol
2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)- Structure
2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)- Chemical Properties
Melting point 278-280 °C (decomp)
density 1.69±0.1 g/cm3(Predicted)
pka0.09±0.20(Predicted)
Safety Information
MSDS Information
2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)- Usage And Synthesis
UsesKRP-199 (compound 14h) is an α-amino-3-hydroxy-5-methylisoxazolepropionic acid receptor (AMPA-R) antagonist (Ki=16 nM) with high potency and selectivity for AMPA-R in vitro and good neuroprotective effects in vivo. KRP-199 can be used in the study of neurodegenerative diseases[1].
References[1] Takano, et al. Design and synthesis of novel 7-heterocycle-6-trifluoromethyl-3-oxoquinoxaline-2-carboxylic acids bearing a substituted phenyl group as superior AMPA receptor antagonists with good physicochemical properties. Bioorganic & medicinal chemistry 14.3 (2006): 776-792. DOI:10.1016/j.bmc.2005.08.060
2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)- Preparation Products And Raw materials
Tag:2-Quinoxalinecarboxylic acid, 7-[4-[[[[(4-carboxyphenyl)amino]carbonyl]oxy]methyl]-1H-imidazol-1-yl]-3,4-dihydro-3-oxo-6-(trifluoromethyl)-(221164-28-9) Related Product Information
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