| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine manufacturers
- AB-MECA
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- $1980.00
-
2026-04-22
- CAS:152918-26-8
- Purity:
- Supply Ability: 10g
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| | N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine Basic information |
| Product Name: | N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine | | Synonyms: | AB-MECA HIGH AFFINITY A3 ADEN;n6-(4-aminobenzyl)-9-[5-(methylcarbonyl)-β-d-ribofuranosyl]adenine;N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine, N6-(4-Aminobenzyl)-9-[5-(methylcarbonyl)-β-D-ribofuranosyl]adenine;β-D-Ribofuranuronamide, 1-[6-[[(4-aminophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-;N6-(4-AMINOBENZYL)-N-METHYLCARBOXAMIDOADENOSINE;ABMECA,AB MECA;AB-MECA, N6-(4-Aminobenzyl)adenosine-5’-N-methyluronamide | | CAS: | 152918-26-8 | | MF: | C18H21N7O4 | | MW: | 399.4 | | EINECS: | | | Product Categories: | | | Mol File: | 152918-26-8.mol |  |
| | N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine Chemical Properties |
| density | 1.68±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble0.3mg/mL | | form | solid | | pka | 12.72±0.70(Predicted) | | color | off-white | | Water Solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.3mg/mL
ethanol: 1mg/mL
DMSO: 10mg/mL
dilute aqueous base: 3.5mg/mL
H2O: insoluble | | InChIKey | LDYMCRRFCMRFKB-MOROJQBDSA-N | | SMILES | CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccc(N)cc4)ncnc23 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine Usage And Synthesis |
| Uses | AB-MECA is a high affinity A3 adenosine receptor agonist. | | Biochem/physiol Actions | High affinity A3 adenosine receptor agonist. | | in vivo | AB-MECA (3 ug/kg; iv) enhances plasma histamine level in mouse[4].
AB-MECA (0.3 mg/kg; iv) enhances antigen-induced bronchoconstriction in male albino guinea pigs, weighing 180-220 g[5].
| Animal Model: | Male Balb/c mice, weighing 18-25 g[4] | | Dosage: | 3 ug/kg | | Administration: | IV; single dose | | Result: | Induced a 5.9-fold increase in histamine levels in murine plasma.
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| | IC 50 | Adenosine A3 receptor |
| | N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine Preparation Products And Raw materials |
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