Co102862 manufacturers
- Co 102862
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- $44.00
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2026-05-16
- CAS:181144-66-1
- Purity: 99.82%
- Supply Ability: 10g
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| | Co102862 Basic information |
| Product Name: | Co102862 | | Synonyms: | Co102862;2-[[4-(4-Fluorophenoxy)phenyl]methylene]hydrazinecarboxamide;(E)-2-(4-(4-fluorophenoxy)benz-ylidene)hydrazinecarboxaMide;[(E)-[4-(4-fluorophenoxy)phenyl]methyleneamino]urea;2-(4-(4-Fluorophenoxy)benzylidene)hydrazinecarboxamide;Hydrazinecarboxamide, 2-[[4-(4-fluorophenoxy)phenyl]methylene]-;V 102862;orally active,V-102862,Co-102862,Co102862,V102862,Co 102862,Inhibitor,Na channels,broad-spectrum,state-dependent,Sodium Channel,inhibit,Na+ channels,anticonvulsant | | CAS: | 181144-66-1 | | MF: | C14H12FN3O2 | | MW: | 273.26 | | EINECS: | | | Product Categories: | | | Mol File: | 181144-66-1.mol |  |
| | Co102862 Chemical Properties |
| density | 1.27±0.1 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | Soluble to 100 mM in DMSO | | form | Powder | | pka | 11.68±0.46(Predicted) | | color | White to off-white |
| | Co102862 Usage And Synthesis |
| Uses | Co 102862 (V 102862) is a potent, broad-spectrum, state-dependent Na+ channel blocker. Co 102862 is also an orally active anticonvulsant[1]. | | Definition | ChEBI: [[4-(4-fluorophenoxy)phenyl]methylideneamino]urea is an aromatic ether. | | Biological Activity | Broad spectrum, state-dependent blocker of voltage-gated sodium channels. Displays ~ 80-fold higher affinity for inactivated Na + channels compared to channels in the resting state. Anticonvulsant; displays activity in rodent models of tonic/clonic and partial-complex seizures. | | storage | Room temperature | | References | [1] Ilyin VI, et al. V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels. Br J Pharmacol. 2005 Mar;144(6):801-12. DOI:10.1038/sj.bjp.0706058 |
| | Co102862 Preparation Products And Raw materials |
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