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Sigma-Aldrich |
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
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| | Anp 1-28, human Basic information |
| Product Name: | Anp 1-28, human | | Synonyms: | ANF 1-28, HUMAN;ANP, ALPHA-, HUMAN;ANP HUMAN, 1-28;ANP (HUMAN, 1-28) (PORCINE, BOVINE, CANINE);ALPHA-ANF (1-28), HUMAN;ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN;a-ANF(1-28), human;M.W. 3080.47 C127H203N45O39S3 | | CAS: | 91917-63-4 | | MF: | C127H205N45O39S3 | | MW: | 3082.46 | | EINECS: | | | Product Categories: | Peptide;Atrial Natriuretic Peptide | | Mol File: | 91917-63-4.mol |  |
| | Anp 1-28, human Chemical Properties |
| density | 1.54±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | form | Lyophilized powder | | Water Solubility | Soluble to 1 mg/ml in water | | Sequence | Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr | | InChIKey | KGZJRXKGJRJKCB-UHFFFAOYSA-N |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | Anp 1-28, human Usage And Synthesis |
| Uses | Atrial natriuretic peptide (ANP) has been used to study its cross reactivity in melanin concentrating hormone (MCH) assay. It has also been used to study its effects in nerve fibres and nerve cell bodies. | | Biochem/physiol Actions | Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis. | | in vivo | ANF-(1-28) (0.5 μg/kg/min) infusion attenuates the rise in plasma creatinine levels by approximately 50% on each day of the study[3]. | | storage | Store at -20°C |
| | Anp 1-28, human Preparation Products And Raw materials |
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