Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester

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Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester manufacturers
Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester Basic information
Product Name:Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester
Synonyms:Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester;Methyl (Z)-2-(5-((2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoate;WAY-272324;PI3Kγ inhibitor 6
CAS:900515-01-7
MF:C16H11NO5S
MW:329.33
EINECS:
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Mol File:900515-01-7.mol
Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester Structure
Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester Chemical Properties
Melting point 190-192 °C(Solv: water (7732-18-5); methanol (67-56-1))
density 1.425±0.06 g/cm3(Predicted)
pka7.20±0.20(Predicted)
Safety Information
MSDS Information
Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester Usage And Synthesis
UsesPI3Kγ inhibitor 6 (compound 9) is a PI3Kγ inhibitor. PI3Kγ inhibitor 6 can be used for the research of inflammatory and autoimmune diseases[1].
References[1] Pomel V, et al. Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma. J Med Chem. 2006 Jun 29;49(13):3857-71. DOI:10.1021/jm0601598
Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester Preparation Products And Raw materials
Tag:Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester(900515-01-7) Related Product Information
4-chloro-3-{5-[(E)-(3-methyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzoic acid Benzoic acid, 2-[5-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-2-furanyl]-, methyl ester (E)-2-(5-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid 3-[5-({3-[2-(4-fluoroanilino)-2-oxoethyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene}methyl)-2-furyl]-2-methylbenzoic acid NVP-BEZ 235 gamma-Glu-Cys trifluoroacetate salt