| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid
CAS:18679-90-8
Package:500mg
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| Company Name: |
Quality Control Solutions Ltd.
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| Tel: |
0755-66853366 13670046396 |
| Email: |
orders@qcsrm.com |
| Products Intro: |
Product Name:Dexpanthenol Impurity 8
CAS:18679-90-8
Purity:95% HPLC Package:10mg;25mg;50mg
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| | Hopantenic Basic information |
| Product Name: | Hopantenic | | Synonyms: | Dexpanthenol iMpurity I;Hopantenic;Butanoic acid, 4-[(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]-, (R)-;Butanoic acid, 4-[[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]amino]-;Butyric acid, 4-(2,4-dihydroxy-3,3-dimethylbutyramido)-, D-(+)- (8CI);D-(+)-Homopantothenic acid;D-Homopantothenic acid;Homopantothenic acid | | CAS: | 18679-90-8 | | MF: | C10H19NO5 | | MW: | 233.26 | | EINECS: | | | Product Categories: | | | Mol File: | 18679-90-8.mol |  |
| | Hopantenic Chemical Properties |
| Melting point | 62-64 °C | | Boiling point | 556.0±50.0 °C(Predicted) | | alpha | D20 +23.8° | | density | 1.230±0.06 g/cm3(Predicted) | | pka | 4.52 at 25° | | form | Oil | | color | Colorless to light yellow |
| HazardClass | IRRITANT | | Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 850, 954, 1575, 1458 i.p.; 2063, 2495, 5940, 7348 s.c.; 6297, 7935, 16810, 13350 orally (Nishizawa) |
| | Hopantenic Usage And Synthesis |
| Uses | HoPan inhibits phosphopantotenoylcysteine synthetase activity. | | Definition | ChEBI: Hopantenic acid is an organooxygen compound and an organonitrogen compound. It is functionally related to a gamma-amino acid. | | References | [1] Mostert KJ, et al. The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. ACS Chem Biol. 2021 Nov 19;16(11):2401-2414. DOI:10.1021/acschembio.1c00535 |
| | Hopantenic Preparation Products And Raw materials |
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