Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt

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Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt Basic information
Product Name:Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt
Synonyms:Hemokinin 1 mouse, rat trifluoroacetate salt;HEK-1 trifluoroacetate salt;Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt
CAS:
MF:C63H101F3N22O17S
MW:1527.67
EINECS:
Product Categories:
Mol File:Mol File
Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt Structure
Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt Chemical Properties
storage temp. −20°C
solubility H2O: soluble
form powder
color white
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
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Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt Usage And Synthesis
DescriptionHemokinin 1 is an 11-amino acid tachykinin neuropeptide with roles in pain transmission and inflammation and is a neurokinin-1 (NK1) receptor agonist.1,2 It is primarily expressed in immune cells and, to a lesser extent, in the brain.3 Hemokinin 1 binds to NK1 receptors (Ki = 0.175 nM) and induces contractions in isolated rat urinary bladder (EC50 = 100 nM).1 Knockdown of Tac4, the gene encoding hemokinin 1, inhibits neurogenic inflammation-induced mechanical and thermal hypersensitivity and visceral nocifensive behavior in mice.3 Tac4-/- mice also exhibit impaired inflammatory responses to intranasal administration of E. coli LPS.4WARNING This product is not for human or veterinary use.
Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt Preparation Products And Raw materials
Tag:Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt Related Product Information
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