N 556 manufacturers
- KY-556
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- $789.00
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2026-07-15
- CAS:110816-78-9
- Purity:
- Supply Ability: 10g
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| Product Name: | N 556 | | Synonyms: | N 556;5,5'-[[2-(Lysyloxy)propane-1,3-diyl]bisoxy]bis[4-oxo-4H-1-benzopyran-2-carboxylic acid ethyl]·2hydrochloride;KY-556;KY556,KY 556 | | CAS: | 110816-78-9 | | MF: | C33H36N2O12.2ClH | | MW: | 725.571 | | EINECS: | | | Product Categories: | | | Mol File: | 110816-78-9.mol |  |
| | N 556 Chemical Properties |
| Melting point | 225-228 °C | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | N 556 Usage And Synthesis |
| Uses | KY-556 is a promising and orally-active pro-agent of disodium cromoglycate (DSCG) against allergic diseases. | | in vivo | The oral anti-allergic effect of KY-556 (N-556) is investigated. N-556 (10-100 mg/kg, p.o.) inhibits dose-dependently the 48-hr homologous passive cutaneous anaphylaxis (PCA) in rats, and the duration of action is longer than that of intravenous Disodium cromoglycate (DSCG). N-556 (20 and 100 mg/kg once a day for 20 consecutive days, p.o.) tends to inhibit the histamine release from actively sensitized rat lung fragments. N-556 (100 mg/kg, p.o.) shows the prolongation of survival time in the rat systemic anaphylaxis. N-556 (100 mg/kg, p.o.) significantly inhibits the increased airway resistance in experimental asthma in rats[1]. | | References | [1] Nakamura S, et al. Effects of N-556 on experimental allergy models in rats. Arerugi. 1990 Dec;39(12):1621-8. PMID:2096808 |
| | N 556 Preparation Products And Raw materials |
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