3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one

3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one Basic information

Product Name:	3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one
Synonyms:	3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one;Steroid sulfatase-IN-8
CAS:	345222-92-6
MF:	C17H21NO5S
MW:	351.42
EINECS:
Product Categories:
Mol File:	345222-92-6.mol

3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one Chemical Properties

Melting point	183-185 °C(Solvent: Tetrahydrofuran ; Hexane)
Boiling point	567.4±60.0 °C(Predicted)
density	1.36±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka	8.27±0.70(Predicted)

Safety Information

MSDS Information

3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one Usage And Synthesis

Uses	Steroid sulfatase-IN-8 (7) is a STS inhibitor with PM IC50 value of 1 nM, JEG-3 IC50 of 0.025 nM, respecively[1].
References	[1] L W Lawrence Woo, et al. Structure-activity relationship for the first-in-class clinical steroid sulfatase inhibitor Irosustat (STX64, BN83495). ChemMedChem. 2011 Nov 4;6(11):2019-34. DOI:10.1002/cmdc.201100288

3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one Preparation Products And Raw materials

Tag:3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one(345222-92-6) Related Product Information

Steroid sulfatase-IN-6 3-Hexyl-5-hydroxy-4,7-dimethyl-2H-chromen-2-one 3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate 2H-1-Benzopyran-2-one, 7-[(aminosulfonyl)oxy]-4-methyl- Steroid sulfatase-IN-5

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