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2,5-Dibromobenzotrifluoride

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2,5-Dibromobenzotrifluoride manufacturers

2,5-Dibromobenzotrifluoride Basic information
Product Name:2,5-Dibromobenzotrifluoride
Synonyms:1,4-DIBROMO-2-TRIFLUOROMETHYL-BENZENE;2,5-Dibromobenzotrifluoride,98%;1,4-Dibromo-2-(trifluoromethyl)benzene, 2,5-Dibromo-alpha,alpha,alpha-trifluorotoluene;1,4-Bibromo-2-(trifluoromethyl)benzene;1,4-Dibromo-2-(trifluoromethyl)benzene, 2,5-Dibromo-alpha,alpha,alpha-t;2,5-DIBROMO-A,A,A-TRIFLUOROTOLUENE;2,5-DIBROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE;2,5-Dibromo Trifluoromethylbenzene
CAS:7657-09-2
MF:C7H3Br2F3
MW:303.9
EINECS:231-620-1
Product Categories:Fluorine series;Aryl;C7;Halogenated Hydrocarbons
Mol File:7657-09-2.mol
2,5-Dibromobenzotrifluoride Structure
2,5-Dibromobenzotrifluoride Chemical Properties
Melting point 49-51 °C(lit.)
Boiling point 47 °C
refractive index 1.52
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to lump
color White to Light yellow
BRN 2261093
InChI1S/C7H3Br2F3/c8-4-1-2-6(9)5(3-4)7(10,11)12/h1-3H
InChIKeyVWKFJAOCLPPQGR-UHFFFAOYSA-N
SMILESFC(F)(F)c1cc(Br)ccc1Br
CAS DataBase Reference7657-09-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39
RIDADR 3276
WGK Germany 3
HazardClass IRRITANT
HS Code 2903998090
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
2,5-Dibromobenzotrifluoride Usage And Synthesis
Uses2,5-Dibromobenzotrifluoride (CAS# 7657-09-2) can be used to prepare for use as anti-cancer agents. It can also be used as a novel anhydride compound to prepare polyamic acid and polyimide.
Uses2,5-Dibromobenzotrifluoride (1,4-Dibromo-2-(trifluoromethyl)benzene) may be used to synthesize 4-bromo-2-(trifluoromethyl)benzaldehyde and functionalized alkynyl-substituted (trifluoromethyl)benzenes.
General Description2,5-Dibromobenzotrifluoride is a halogenated hydrocarbon.
Synthesis
4-Bromo-3-(trifluoromethyl)aniline

393-36-2

2,5-DIBROMOBENZOTRIFLUORIDE

7657-09-2

The general procedure for synthesizing 2,5-dibromotrifluorobenzene from 5-amino-2-bromobenzotrifluoride was as follows: first, a diazonium salt solution was prepared according to the method described in Example 3. Subsequently, the cooled diazonium salt solution was rapidly poured into a pre-cooled and well-stirred mixture of CuBr (13 g, 0.091 mol) and concentrated hydrobromic acid (71 g, 0.44 mol). The reaction mixture was slowly warmed to room temperature and stirred continuously for 2 to 3 hours. Finally, the reaction system was heated to 60-70 °C and the target product 2,5-dibromotrifluorobenzene was obtained upon completion of the reaction. The yield was 63%.

References[1] Patent: WO2016/63300, 2016, A1. Location in patent: Page/Page column 9
2,5-Dibromobenzotrifluoride Preparation Products And Raw materials
Raw materials4-Bromo-3-(trifluoromethyl)aniline-->Cuprous bromide-->Hydrogen bromide-->Sodium nitrite-->Hydrochloric acid
Preparation ProductsPyridine, 4,4'-[2-(trifluoromethyl)-1,4-phenylene]bis-
Tag:2,5-Dibromobenzotrifluoride(7657-09-2) Related Product Information
2-Chlorotoluene Styrene Fluorobenzene 2,4-Dibromo-6-(trifluoromethyl)aniline 2,6-Dibromo-4-(trifluoromethyl)aniline 2,5-Dibromobenzotrifluoride 1,4-Dibromobenzene 3-Bromobenzotrifluoride 2,5-Dibromotoluene 2,3,5-Tribromobenzotrifluoride 1-Bromo-2-difluoromethylbenzene 3-Chloro-2,5-dibromobenzotrifluoride 2-Chloro-3,5-dibromobenzotrifluoride 3-Chloro-4,5-dibromobenzotrifluoride 2.5-Dibromobenzotrifluoride 10g [r] 3,5-Dibromobenzotrifluoride 1,2-Dibromo-3-trifluoromethyl-benzene ADBTF/ 4-Amino-3,5-dibromobenzotrifluoride