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| | 3-(Bromomethyl)benzo[b]thiophene Basic information |
| | 3-(Bromomethyl)benzo[b]thiophene Chemical Properties |
| Boiling point | 311.3±17.0 °C(Predicted) | | density | 1.593±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | form | solid | | InChI | 1S/C9H7BrS/c10-5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6H,5H2 | | InChIKey | WYKHJZSILIVQKU-UHFFFAOYSA-N | | SMILES | BrCC1=CSC2=C1C=CC=C2 |
| HS Code | 2934208090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | 3-(Bromomethyl)benzo[b]thiophene Usage And Synthesis |
| Synthesis | B. Phosphorus tribromide (PBr3, 0.23 mL, 2.42 mmol) was added slowly and dropwise to a stirring solution of benzothiophene-3-ylmethanol (400 mg, 2.44 mmol) in ether (12 mL) at 0 °C. The reaction mixture was continued to be stirred at 0 °C for 30 min, then brought to room temperature and held for 45 min. The reaction mixture was poured into a mixture of ice water and ether, and the organic phase was separated, washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 3-(bromomethyl)benzo[b]thiophene as a light-colored solid (404 mg, 73% yield). | | References | [1] Patent: WO2008/110793, 2008, A1. Location in patent: Page/Page column 111
[2] Patent: US2009/176996, 2009, A1. Location in patent: Page/Page column 15-16 |
| | 3-(Bromomethyl)benzo[b]thiophene Preparation Products And Raw materials |
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